Compare Estazolam vs. Silenor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prosom
(estazolam)

Silenor
(doxepin)

Helps you stay asleep longer. Prosom (estazolam) can help you sleep, but you might feel hungover the next day.Helps you relax, and sleep. Doxepin is a non-addictive way to help people stay asleep, but it comes with a list of side effects.
Reviews & ratings
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Have you used Prosom (estazolam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Silenor (doxepin)?
Worth itNot sureNot worth it
Side effects
EstazolamSilenor
  • Sleepiness 15%
  • Weakness 3%
  • Difficulty controlling muscles 4%
  • Dizziness 4%
  • Abnormal coordination 3%
  • Leg and foot pain 1%
More Estazolam side effects »

We haven’t found good data for Silenor side effects.

FDA side effect reports for Silenor »
How it works
EstazolamSilenor
Prosom (estazolam) is a benzodiazepine. It helps you stay asleep by improving the quality of your sleep so you don't wake up as much at night.Doxepin is a tricyclic antidepressant. It keeps norepinephrine and serotonin in your brain longer, helping you relax, and sleep. It also blocks the chemical that causes itch, and wakefulness.
Type of medication
EstazolamSilenor
Prescription only
Available as
EstazolamSilenor
  • Pill
  • Pill
  • Liquid
Used for
EstazolamSilenor
  • Alcoholism Anxiety Depression Anxiety Depression Anxiety Depression Psychoneurotic Personality Disorder Insomnia Pruritus Moderate
Risk factors for serious side effects
EstazolamSilenor
  • Using Prosom (estazolam) for more than 10 days
  • Drinking alcohol
  • Taking sedative medicines
  • People age 65 or older
Detailed Prosom (estazolam) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    EstazolamSilenor
    No interactions related info.
    • Doxepin can interact with many different medications, vitamins, and alternative treatments.
    Alcohol
    EstazolamSilenor
    • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
    • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
    Weight
    EstazolamSilenor
    No weight related info.
    • Doxepin can increase your appetite, leading to weight gain.
    Upsides and benefits
    EstazolamSilenor
    • Prosom (estazolam) is available in generic.
    • In a clinical trial Doxepin was able to significantly improve sleep quality.
    • Doxepin helps improve your appetite, energy level, and sense of well-being, which increases your interests.
    • Once your body gets used to Doxepin, most of the side effects go away.
    • Doxepin comes in a generic form, so it is pretty cheap.
    • Doxepin is not addictive.
    Downsides and risks
    EstazolamSilenor
    • Prosom (estazolam) isn't recommended if you're age 65 or older because the side effects can be more intense.
    • You can become dependent on Prosom (estazolam) if you take it for more than a few weeks.
    • If you stop Prosom (estazolam) suddenly after taking it for a while, your insomnia might come back even worse than when you started.
    • Some people taking Doxepin walk, drive, eat, and have sex while sleeping. Be sure to tell your doctor if this happens to you.
    • Doxepin can increase your appetite, leading to weight gain.
    • Taking Doxepin can make emptying your bladder difficult.
    • Some people have suicidal thoughts when taking Doxepin.
    • Doxepin can interact with many different medications, vitamins, and alternative treatments.
    Tips from our pharmacists for people taking the medication
    EstazolamSilenor
    • Don't take Prosom (estazolam) unless you know you'll be going to sleep right away.
    • Make sure you can sleep for at least 8 hours before you take it.
    • Prosom (estazolam) works best if you develop good sleeping habits.
    • Take Prosom (estazolam) for the shortest amount of time needed to treat your insomnia since it can be addicting.
    • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
    • Take Doxepin 30 minutes before bedtime so it starts working when you get in bed.
    • Avoid activities that need you to be fully alert like driving, until you know how Doxepin affects you.
    • Follow up with your doctor so he or she can make sure Doxepin is the right medication for your depression.
    • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
    • Some people get dry mouth, or constipation when taking Doxepin. Sugar free gum or candy can help the dry mouth, and drinking more fluid can help with constipation.
    • Avoid direct sunlight while taking this medication. When you can’t avoid it, be sure to use sunscreen. It’s also important to put on a long-sleeved shirt, pants, hat, and sunglasses.
    Learn more
    More about EstazolamSide effectsAlternativesFDA package insert
    Have you used Prosom (estazolam)?
    Worth itNot sureNot worth it
    More about SilenorSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Silenor (doxepin)?
    Worth itNot sureNot worth it