Compare Farxiga vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Farxiga
(dapagliflozin)

Glucotrol XL
(glipizide)

Lowers blood sugar. Farxiga (dapagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.Lowers blood sugar. Glucotrol XL (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low, so you must always carry some form of sugar with you that can be readily used.
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Coupons for Farxiga
Best available price for 30 (10mg) tablets of farxiga
Coupons for Glucotrol
Best available price for 60 (5mg) tablets of glucotrol
Reviews & ratings
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Have you used Farxiga (dapagliflozin)?
Worth itNot sureNot worth it
Reviews for Glucotrol
50%
-50% worse vs. Farxiga
32%
-32% worse vs. Farxiga
19%
+19% better vs. Farxiga
332 reviews
Have you used Glucotrol XL (glipizide)?
Worth itNot sureNot worth it
Side effects
FarxigaGlucotrol
  • Female yeast infection 6%
  • Common cold symptoms 1%
  • Urinary tract infection 2%
  • Increased urination 1%
  • Male yeast infection 3%
  • Nausea 1%
  • Flu 1%
More Farxiga side effects »
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Low blood sugar 3%
  • Constipation 3%
  • Nausea 3%
  • Headache 2%
More Glucotrol side effects »
How it works
FarxigaGlucotrol
Farxiga (dapagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.Glucotrol XL (glipizide) stimulates your body to release insulin and lower blood sugar.
Type of medication
FarxigaGlucotrol
Prescription onlyPrescription only
Available as
FarxigaGlucotrol
  • Pill
  • Pill
  • Extended release pill
Used for
FarxigaGlucotrol
Risk factors for serious side effects
FarxigaGlucotrol
  • Taking water pills for blood pressure
  • Over age 65
  • Kidney problems
  • Kidney damage
  • Taking water pills, ACE inhibitors or ARBs for blood pressure
Detailed Farxiga (dapagliflozin) risks & warnings »
  • Skipping meals or having inconsistent meal times
  • Drinking alcohol
  • Using other blood sugar-lowering medicine
  • People age 60 or older
  • Those with kidney and/or liver problems
Detailed Glucotrol XL (glipizide) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
FarxigaGlucotrol
  • Not a good choice if you drink a lot of alcohol.
  • Avoid drinking alcohol while taking Glucotrol XL (glipizide).
Food
FarxigaGlucotrol
  • Take once in the morning with or without food.
  • Eat regular and well-balanced meals to keep your blood sugar levels normal.
Kidneys and liver
FarxigaGlucotrol
  • Farxiga (dapagliflozin) can cause or worsen kidney problems. If you already have severe kidney damage, you can't take Farxiga (dapagliflozin). You're more likely to have this happen if you're on certain medicines to lower your blood pressure or anti-inflammatory medicines (NSAIDs), have heart failure or mild kidney damage. Your doctor will have you do regular blood tests to make sure your kidneys are healthy.
  • People with kidney and/or liver problems take a longer time to get rid of Glucotrol XL (glipizide) from their body. They are more sensitive to the effects of low blood sugar that include symptoms such as fast heartbeat, sweating, pale skin, shakiness, confusion and irritability. They need to make sure to carry with them some form of sugar such as hard candies or glucose tablets at all times while they are on this medicine.
  • Can be used in those with kidney problems.
Pain
FarxigaGlucotrol
  • Tell your doctor right away if you have blood in urine, or pain when you urinate.
No pain related info.
Weight
FarxigaGlucotrol
  • Can help you lose weight.
  • Can cause mild weight gain of 2 to 3 pounds on average.
Upsides and benefits
FarxigaGlucotrol
  • Can lower A1c by 1% (A1c measures your average blood sugar over time.)
  • Can help you lose weight.
  • Less chance of low blood sugar than other diabetes medicines.
  • Lowers A1c levels by 1-2%. (A1c is a test that measures your average blood sugars over the past 3 months).
  • Glucotrol XL (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
  • Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
  • Can be used in those with kidney problems.
  • Available as a generic form and is relatively cheap.
Downsides and risks
FarxigaGlucotrol
  • Not a first choice medicine for diabetes because it doesn't lower blood sugar as much as other medicines.
  • Higher risk of genital yeast infections and urinary tract infections.
  • This is an expensive medication with no generic available at this time.
  • Not shown to improve cardiovascular outcomes like other similar medicines because it can increase cholesterol.
  • Not a good choice if you drink a lot of alcohol.
  • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
  • While taking Glucotrol XL (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
  • Can cause mild weight gain of 2 to 3 pounds on average.
  • Might lose its effectiveness over time.
  • Needs to be taken 30 minutes before a meal for it to be most effective.
Tips from our pharmacists for people taking the medication
FarxigaGlucotrol
  • Take once in the morning with or without food.
  • Farxiga (dapagliflozin) can cause you to urinate more, so be sure to stay hydrated.
  • Can cause genital yeast infections in females and males.
  • Can cause urinary tract infections (UTI).
  • Do not take if you have kidney problems or bladder cancer.
  • Tell your doctor right away if you have blood in urine, or pain when you urinate.
  • Take the medicine 30 minutes before eating, usually before your first big meal of the day.
  • Avoid drinking alcohol while taking Glucotrol XL (glipizide).
  • Eat regular and well-balanced meals to keep your blood sugar levels normal.
  • Check your blood sugar regularly.
  • Glucotrol XL (glipizide) can cause dizziness so avoid activities that require coordination until you know how your body can handle the medicine.
Learn more
More about FarxigaSide effectsAlternativesFDA package insert
Have you used Farxiga (dapagliflozin)?
Worth itNot sureNot worth it
More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Glucotrol XL (glipizide)?
Worth itNot sureNot worth it