Compare Farxiga vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Farxiga
(dapagliflozin)

Diabeta
(glyburide)

Lowers blood sugar. Farxiga (dapagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.Lowers blood sugar. Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
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Coupons for Farxiga
Best available price for 30 (10mg) tablets of farxiga
Coupons for glyburide
Best available price for 60 (5mg) tablets of glyburide
Reviews & ratings
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Have you used Farxiga (dapagliflozin)?
Worth itNot sureNot worth it
Reviews for glyburide
45%
-45% worse vs. Farxiga
34%
-34% worse vs. Farxiga
21%
+21% better vs. Farxiga
110 reviews
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it
Side effects
Farxigaglyburide
  • Female yeast infection 6%
  • Common cold symptoms 1%
  • Urinary tract infection 2%
  • Increased urination 1%
  • Male yeast infection 3%
  • Nausea 1%
  • Flu 1%
More Farxiga side effects »
  • Nausea and heartburn 2%
  • Skin allergies 2%
More glyburide side effects »
How it works
Farxigaglyburide
Farxiga (dapagliflozin) is an anti-diabetes medication. It lowers blood sugar by causing your body to get rid of sugar in your urine.Diabeta (glyburide) stimulates your body to release insulin and lower blood sugar.
Type of medication
Farxigaglyburide
Prescription onlyPrescription only
Available as
Farxigaglyburide
  • Pill
  • Pill
Used for
Farxigaglyburide
Risk factors for serious side effects
Farxigaglyburide
  • Taking water pills for blood pressure
  • Over age 65
  • Kidney problems
  • Kidney damage
  • Taking water pills, ACE inhibitors or ARBs for blood pressure
Detailed Farxiga (dapagliflozin) risks & warnings »
  • Over age 65
  • Kidney problems
  • Use of other blood sugar lowering medicines
  • Alcohol
  • Intense physical activity
Detailed Diabeta (glyburide) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
Farxigaglyburide
  • Not a good choice if you drink a lot of alcohol.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Food
Farxigaglyburide
  • Take once in the morning with or without food.
  • Eat well-balanced meals to avoid low blood sugar.
Kidneys and liver
Farxigaglyburide
  • Farxiga (dapagliflozin) can cause or worsen kidney problems. If you already have severe kidney damage, you can't take Farxiga (dapagliflozin). You're more likely to have this happen if you're on certain medicines to lower your blood pressure or anti-inflammatory medicines (NSAIDs), have heart failure or mild kidney damage. Your doctor will have you do regular blood tests to make sure your kidneys are healthy.
  • Not ideal for elderly or those with poor kidney function.
Pain
Farxigaglyburide
  • Tell your doctor right away if you have blood in urine, or pain when you urinate.
No pain related info.
Weight
Farxigaglyburide
  • Can help you lose weight.
  • Can cause weight gain, dizziness, or stomach upset.
  • Can cause weight gain (about 2 to 3 pounds).
Upsides and benefits
Farxigaglyburide
  • Can lower A1c by 1% (A1c measures your average blood sugar over time.)
  • Can help you lose weight.
  • Less chance of low blood sugar than other diabetes medicines.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides and risks
Farxigaglyburide
  • Not a first choice medicine for diabetes because it doesn't lower blood sugar as much as other medicines.
  • Higher risk of genital yeast infections and urinary tract infections.
  • This is an expensive medication with no generic available at this time.
  • Not shown to improve cardiovascular outcomes like other similar medicines because it can increase cholesterol.
  • Not a good choice if you drink a lot of alcohol.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Tips from our pharmacists for people taking the medication
Farxigaglyburide
  • Take once in the morning with or without food.
  • Farxiga (dapagliflozin) can cause you to urinate more, so be sure to stay hydrated.
  • Can cause genital yeast infections in females and males.
  • Can cause urinary tract infections (UTI).
  • Do not take if you have kidney problems or bladder cancer.
  • Tell your doctor right away if you have blood in urine, or pain when you urinate.
  • Check your blood sugar regularly.
  • Eat well-balanced meals to avoid low blood sugar.
  • Works best if you take it 30 minutes before first main meal of the day.
  • Can cause weight gain, dizziness, or stomach upset.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Learn more
More about FarxigaSide effectsAlternativesFDA package insert
Have you used Farxiga (dapagliflozin)?
Worth itNot sureNot worth it
More about glyburideSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it