Compare felodipine vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Plendil
(felodipine)

Lopressor
(metoprolol tartrate)

Lowers blood pressure. Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.
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Coupons for felodipine
Best available price for 30 (10mg) tablets of plendil
Coupons for Lopressor
Best available price for 60 (25mg) tablets of lopressor
Reviews & ratings
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Have you used Plendil (felodipine)?
Worth itNot sureNot worth it
Reviews for Lopressor
62%
-62% worse vs. felodipine
47%
-47% worse vs. felodipine
15%
+15% better vs. felodipine
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Side effects
felodipineLopressor
  • Headache 1%
  • Flushing 3%
  • Upset stomach 3%
  • Weakness 1%
  • Colds or flu 2%
  • Runny nose 2%
  • Sneezing 2%
  • Rash 1%
More felodipine side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
felodipineLopressor
Plendil (felodipine) is a calcium channel blocker. It lowers blood pressure by relaxing heart tissue and lowering pressure in blood vessels, which causes your blood pressure to go down.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
felodipineLopressor
Prescription onlyPrescription only
Available as
felodipineLopressor
  • Extended release
  • Pill
Used for
felodipineLopressor
Risk factors for serious side effects
felodipineLopressor
  • Over age 65
  • Taking in combination with a beta-blocker
  • Liver disease
  • History of heart failure
Detailed Plendil (felodipine) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
felodipineLopressor
  • Plendil (felodipine) can be taken without food or with a light low fat meal.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
Pain
felodipineLopressor
No pain related info.
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
Upsides and benefits
felodipineLopressor
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
Downsides and risks
felodipineLopressor
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
felodipineLopressor
  • Can cause swelling in your legs or ankles.
  • Can also cause swelling in your gums.
  • Plendil (felodipine) can be taken without food or with a light low fat meal.
  • Avoid grapefruit and grapefruit juice while taking Plendil (felodipine).
  • You might feel lightheaded or dizzy when first starting Plendil (felodipine).
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
Learn more
More about felodipineSide effectsAlternativesFDA package insert
Have you used Plendil (felodipine)?
Worth itNot sureNot worth it
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it