Compare Fioricet vs. Fiorinal

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Fioricet
(Butalbital / Acetaminophen / Caffeine)

Fiorinal
(Butalbital / Aspirin / Caffeine)

Treats tension headaches. Fioricet (Butalbital / Acetaminophen / Caffeine) works well for tension headaches, but isn’t recommended due to the ability to overuse it and have withdrawal symptoms.Coming soon.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Fioricet (Butalbital / Acetaminophen / Caffeine)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Fiorinal (Butalbital / Aspirin / Caffeine)?
Worth itNot sureNot worth it
Side effects
FioricetFiorinal

We haven’t found good data for Fioricet side effects.

FDA side effect reports for Fioricet »

We haven’t found good data for Fiorinal side effects.

FDA side effect reports for Fiorinal »
How it works
FioricetFiorinal
Fioricet (Butalbital / Acetaminophen / Caffeine) is a combination of three medications. Butalbital is a barbiturate that relaxes you. Acetaminophen relieves pain, and caffeine narrows the blood vessels that otherwise cause headaches.Coming soon.
Type of medication
FioricetFiorinal
Pain reliever
Barbiturate
Prescription only
Coming soon.
Available as
FioricetFiorinal
  • Pill
  • Oral solution
  • Pill
Used for (click to learn more)
FioricetFiorinal
  • Tension-type headache
Risk factors for serious side effects
FioricetFiorinal
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other acetaminophen-containing medicines
  • History of liver disease
    Detailed Fioricet (Butalbital / Acetaminophen / Caffeine) risks & warnings »
    Coming soon.
    Pregnancy category
    FioricetFiorinal
    Alcohol
    • While taking Fioricet (Butalbital / Acetaminophen / Caffeine), don’t drink alcohol or take other drugs that slow your body down.
    No specific alcohol related info.
    Upsides and benefits
    FioricetFiorinal
    • Fioricet (Butalbital / Acetaminophen / Caffeine) works better and faster in treating tension headaches than the combination of acetaminophen and codeine.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) doesn’t cost much since it's available as a generic medication.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) has very few side effects.
    • It has been widely used for a long time.
    Coming soon.
    Downsides and risks
    FioricetFiorinal
    • Fioricet (Butalbital / Acetaminophen / Caffeine) isn't the first choice medication for treating tension headaches.
    • It's not a good medication for long-term use.
    • Overuse of Fioricet (Butalbital / Acetaminophen / Caffeine) can lead to chronic tension headaches.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) can cause dangerous withdrawal symptoms, intoxication, and dependence.
    • Taking Fioricet (Butalbital / Acetaminophen / Caffeine) can decrease your ability to drive a car, or operate machinery.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    FioricetFiorinal
    • Take Fioricet (Butalbital / Acetaminophen / Caffeine) as soon as your headache starts, then lie down in a dark room to help ease the pain.
    • Be sure to take each dose with a full glass of water.
    • Take your time getting up from sitting or lying down while taking Fioricet (Butalbital / Acetaminophen / Caffeine) to decrease your chances of feeling dizzy.
    • Be sure to limit how much caffeine and chocolate you take while on Fioricet (Butalbital / Acetaminophen / Caffeine) since it can cause nervousness, shakiness, and a fast heartbeat.
    • While taking Fioricet (Butalbital / Acetaminophen / Caffeine), don’t drink alcohol or take other drugs that slow your body down.
    • Don't take other forms of acetaminophen (Tylenol) while taking Fioricet (Butalbital / Acetaminophen / Caffeine), since taking too much can lead to liver problems.
    Coming soon.
    Learn more
    More about FioricetSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Fioricet (Butalbital / Acetaminophen / Caffeine)?
    Worth itNot sureNot worth it
    More about FiorinalSide effectsReviews & ratingsFDA package insert
    Have you used Fiorinal (Butalbital / Aspirin / Caffeine)?
    Worth itNot sureNot worth it