Compare Fioricet vs. Zomig

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Fioricet
(Butalbital / Acetaminophen / Caffeine)

Zomig
(Zolmitriptan)

Treats tension headaches. Fioricet (Butalbital / Acetaminophen / Caffeine) works well for tension headaches, but isn’t recommended due to the ability to overuse it and have withdrawal symptoms.Coming soon.
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Reviews & ratings
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Side effects
FioricetZomig

We haven’t found good data for Fioricet side effects.

FDA side effect reports for Fioricet »

We haven’t found good data for Zomig side effects.

FDA side effect reports for Zomig »
How it works
FioricetZomig
Fioricet (Butalbital / Acetaminophen / Caffeine) is a combination of three medications. Butalbital is a barbiturate that relaxes you. Acetaminophen relieves pain, and caffeine narrows the blood vessels that otherwise cause headaches.Coming soon.
Type of medication
FioricetZomig
Pain reliever
Barbiturate
Prescription only
Coming soon.
Available as
FioricetZomig
  • Pill
  • Oral solution
  • Pill
  • Dissolving tablet
  • Nasal spray
Used for (click to learn more)
FioricetZomig
  • Migraine (Acute)
Risk factors for serious side effects
FioricetZomig
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other acetaminophen-containing medicines
  • History of liver disease
    Detailed Fioricet (Butalbital / Acetaminophen / Caffeine) risks & warnings »
    Coming soon.
    Pregnancy category
    FioricetZomig
    Alcohol
    • While taking Fioricet (Butalbital / Acetaminophen / Caffeine), don’t drink alcohol or take other drugs that slow your body down.
    No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    FioricetZomig
    • Fioricet (Butalbital / Acetaminophen / Caffeine) works better and faster in treating tension headaches than the combination of acetaminophen and codeine.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) doesn’t cost much since it's available as a generic medication.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) has very few side effects.
    • It has been widely used for a long time.
    Coming soon.
    Downsides and risks
    FioricetZomig
    • Fioricet (Butalbital / Acetaminophen / Caffeine) isn't the first choice medication for treating tension headaches.
    • It's not a good medication for long-term use.
    • Overuse of Fioricet (Butalbital / Acetaminophen / Caffeine) can lead to chronic tension headaches.
    • Fioricet (Butalbital / Acetaminophen / Caffeine) can cause dangerous withdrawal symptoms, intoxication, and dependence.
    • Taking Fioricet (Butalbital / Acetaminophen / Caffeine) can decrease your ability to drive a car, or operate machinery.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    FioricetZomig
    • Take Fioricet (Butalbital / Acetaminophen / Caffeine) as soon as your headache starts, then lie down in a dark room to help ease the pain.
    • Be sure to take each dose with a full glass of water.
    • Take your time getting up from sitting or lying down while taking Fioricet (Butalbital / Acetaminophen / Caffeine) to decrease your chances of feeling dizzy.
    • Be sure to limit how much caffeine and chocolate you take while on Fioricet (Butalbital / Acetaminophen / Caffeine) since it can cause nervousness, shakiness, and a fast heartbeat.
    • While taking Fioricet (Butalbital / Acetaminophen / Caffeine), don’t drink alcohol or take other drugs that slow your body down.
    • Don't take other forms of acetaminophen (Tylenol) while taking Fioricet (Butalbital / Acetaminophen / Caffeine), since taking too much can lead to liver problems.
    Coming soon.
    Learn more
    More about FioricetSide effectsReviews & ratingsAlternativesFDA package insert
    More about ZomigSide effectsReviews & ratingsFDA package insert