Compare Fiorinal vs. Imitrex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Fiorinal
(butalbital / aspirin / caffeine)

Imitrex
(sumatriptan)

Coming soon.Treats migraine headaches. Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.
Reviews & ratings
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Have you used Fiorinal (butalbital / aspirin / caffeine)?
Worth itNot sureNot worth it
Reviews for Imitrex
74%
+26% better vs. Fiorinal
68%
+32% better vs. Fiorinal
19%
+19% better vs. Fiorinal
Have you used Imitrex (sumatriptan)?
Worth itNot sureNot worth it
Side effects
FiorinalImitrex

We haven’t found good data for Fiorinal side effects.

FDA side effect reports for Fiorinal »
  • Pain and other pressure sensations 2%
  • Atypical sensations 1%
  • Paresthesia (all types) 1%
  • Sensation warm/cold 1%
  • Pain - location specified 1%
  • Malaise/fatigue 2%
  • Chest - pain/tightness/pressure and/or heaviness 1%
  • Neck/throat/jaw - pain/ tightness/pressure 2%
  • Other - pressure/tightness/ heaviness 1%
  • Vertigo 2%
More Imitrex side effects »
How it works
FiorinalImitrex
Coming soon.Imitrex (Sumatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.
Type of medication
FiorinalImitrex
Prescription only
Available as
FiorinalImitrex
  • Pill
  • Pill
  • Injection
  • Nasal spray
Used for
FiorinalImitrex
  • Tension Type Headache
Risk factors for serious side effects
FiorinalImitrex
    Coming soon.
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    Detailed Imitrex (sumatriptan) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Sleep
    FiorinalImitrex
    No sleep related info.
    • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
    Upsides and benefits
    FiorinalImitrex
    Coming soon
    • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
    • A combination of forms can be used if symptoms do not improve.
    • The nasal spray and injectable forms work very quickly.
    • It's generally safe to use if you are pregnant.
    • Comes in a generic form, so it can be pretty cheap.
    Downsides and risks
    FiorinalImitrex
    Coming soon
    • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
    • Does not prevent migraine headaches; it only treats them once they start.
    • Must wait 1 hour before using second injection.
    • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
    • Need to have your blood pressure checked often, especially if you're pregnant.
    Tips from our pharmacists for people taking the medication
    FiorinalImitrex
    Coming soon
    • Take it as soon as your headache starts.
    • If you use the nasal spray, be sure to blow your nose before using it.
    • If you use the patch, put it on a dry area free of scars, tattoos, or other cuts and scrapes. Be sure to press the button to activate it.
    • If you use the injection, you can use a second injection if you still have a headache after an hour. If you have symptoms 2 hours after the injection, switch to the pill version.
    • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
    • Lie down in a dark room after taking Imitrex (Sumatriptan) to help ease the pain.
    Learn more
    More about FiorinalSide effectsReviews & ratingsFDA package insert
    Have you used Fiorinal (butalbital / aspirin / caffeine)?
    Worth itNot sureNot worth it
    More about ImitrexSide effectsReviews & ratingsFDA package insert
    Have you used Imitrex (sumatriptan)?
    Worth itNot sureNot worth it