Compare Flexeril vs. Norflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flexeril (cyclobenzaprine)

Prescription only
Relaxes your muscles.

Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.

4.7/ 7 average rating with 1064 reviewsforFlexeril
No information currently available
  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women, but talk to your doctor about it first.
No information currently available
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with heart conditions (like rhythm problems, heart failure, or recent heart attack).
  • Can make you have dry mouth.
  • Not effective for muscle spasms caused by brain or spinal injuries.
No information currently available
Used for
  • Musculoskeletal pain
Dosage forms
  • Pill
  • Liquid
  • Extended release
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Side effects
4possible side effects
  • Dry mouth
  • Dizziness
  • Fatigue
  • Nausea
See more detailed side effects
The Norflex (Orphenadrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Serotonin syndrome

    Taking monoamine oxidase inhibitors (MAOI)

    ...and 1 more risk factors

  • Dizziness and sleepiness

    Alcohol or drug use

    ...and 1 more risk factors

  • Heart attack or stroke

    Recent heart attack

    ...and 2 more risk factors

  • Dehydration

    Older than 65 years

    ...and 1 more risk factors

  • Overactive Thyroid

    Overactive thyroid

See more detailed risks and warnings
No information currently available