Compare Flexeril vs. Soma

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flexeril
(Cyclobenzaprine)

Soma
(Carisoprodol)

Relaxes your muscles. Flexeril (Cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.Relaxes your muscles. Soma (Carisoprodol) is widely used to treat muscle spasms and is available as a generic, but it's not considered a first-choice treatment for muscle spasms. It's also not meant for long-term therapy.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.682646212847555Flexeril
Reviews for Flexeril (Cyclobenzaprine)
66%
of people say Flexeril (Cyclobenzaprine) is worth it
37%
say it works well
14%
say it's a big hassle
Reviews for Soma (Carisoprodol)
59%
7% vs. Flexeril (Cyclobenzaprine)
36%
1% vs. Flexeril (Cyclobenzaprine)
10%
+4% vs. Flexeril (Cyclobenzaprine)
Side effects
FlexerilSoma
  • Indigestion 3%
  • Fatigue 1%
More Flexeril side effects »
  • Drowsiness 11%
  • Dizziness 6%
  • Hedache 3%
  • Any side effect 2%
More Soma side effects »
How it works
FlexerilSoma
Flexeril (Cyclobenzaprine) is a muscle relaxer. It works in the brain to help calm down muscle spasms without interfering with normal muscle function.Soma (Carisoprodol) is a muscle relaxant. It works in the brain to help calm down muscle spasms.
Type of medication
FlexerilSoma
Muscle relaxerPrescription only
Muscle relaxerPrescription only
Available as
FlexerilSoma
  • Pill
  • Extended release
  • Pill
Used for (click to learn more)
FlexerilSoma
Risk factors for serious side effects
FlexerilSoma
  • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
  • Taking other medications for your mood
  • Alcohol or drug use
  • Age over 65
  • Taking tramadol
Detailed Flexeril (Cyclobenzaprine) risks & warnings »
  • Taking other medications that also cause sleepiness
  • Recreational drug use
  • Excessive alcohol use
  • Prior history of drug abuse
  • Prior history of overdoses of drugs of abuse, recreational drugs or alcohol
Detailed Soma (Carisoprodol) risks & warnings »
Pregnancy category
FlexerilSoma
BFDA pregnancy category (Probably safe)

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
  • Don't drink alcohol while on this medication.
  • Taking Flexeril (Cyclobenzaprine) may make you feel dizzy or sleepy for the first few days, especially if you drink a lot of alcohol or take recreational drugs. Your body should adjust to this, however, avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.
  • Don't drink alcohol while on this medication.
  • Taking Soma (Carisoprodol) can make you feel sleepy and dizzy, especially if you're taking other medications that can also make you feel sleepy, or if you're taking recreational drugs or drinking too much alcohol. Avoid driving or doing other tasks that require concentration until you know how this medication affects you. Get up very slowly from a seated or lying down position.
  • There have been reports of seizures in people taking Soma (Carisoprodol). However, this has been rare and only reported in people who were also overdosing on other medications, recreational drugs or alcohol.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
FlexerilSoma
  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women.
  • Available in generic.
  • Available in two different strengths, although the smaller strength is only available as brand name and thus more expensive.
Downsides and risks
FlexerilSoma
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with recent heart issues (like rhythm problems, heart failure, or heart attack).
  • Can cause dizziness and sleepiness.
  • Not first line for treating muscle spasms.
  • Not meant for long term therapy.
  • Can cause dependence and withdrawal symptoms if you stop taking it suddenly.
  • Can cause dizziness and sleepiness.
Tips from our pharmacists for people taking the medication
FlexerilSoma
  • Not to be used for long-term treatment.
  • Can cause dizziness, fatigue, and sleepiness.
  • Take the medication at the same time each day.
  • Don't drink alcohol while on this medication.
  • Not to be used for long-term treatment (2 to 3 weeks maximum)
  • Can cause stomach pain, nausea and vomiting.
  • Can cause dizziness, fatigue, and sleepiness.
  • Take the medication at the same time each day.
  • Don't drink alcohol while on this medication.
Learn more
More about FlexerilSide effectsReviews & ratingsAlternativesFDA package insert
More about SomaSide effectsReviews & ratingsAlternativesFDA package insert