Compare Flexeril vs. Soma

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flexeril
(cyclobenzaprine)

Soma
(carisoprodol)

Relaxes your muscles. Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.Relaxes your muscles. Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.69Flexeril
Reviews for Flexeril
66%
of people (All ages) say Flexeril is worth it
37%
say it works well
14%
say it's a big hassle
1064 reviews
Have you used Flexeril (cyclobenzaprine)?
Worth itNot sureNot worth it
Reviews for Soma
61%
+5% better vs. Flexeril
39%
-2% worse vs. Flexeril
9%
-5% worse vs. Flexeril
220 reviews
Have you used Soma (carisoprodol)?
Worth itNot sureNot worth it
Side effects
FlexerilSoma
  • Dizziness 1%
  • Fatigue 1%
  • Nausea 2%
  • Dry mouth 4%
  • Sleepiness 2%
  • Constipation 3%
  • Blurry vision 3%
  • Indigestion 3%
  • Change in taste 6%
  • Rapid heartbeat 6%
More Flexeril side effects »
  • Headache 3%
  • Dizziness 6%
  • Drowsiness 7%
More Soma side effects »
How it works
FlexerilSoma
Flexeril (cyclobenzaprine) is a muscle relaxer. It works in the brain to help calm down muscle spasms without interfering with normal muscle function.Soma (carisoprodol) is a muscle relaxant. It works in the brain to help calm down muscle spasms.
Type of medication
FlexerilSoma
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
FlexerilSoma
  • Pill
  • Liquid
  • Pill
Used for
FlexerilSoma
Risk factors for serious side effects
FlexerilSoma
  • Taking monoamine oxidase inhibitors (MAOI)
  • Taking other medications for your mood
  • Alcohol or drug use
  • Age over 65 years
  • Recent heart attack
Detailed Flexeril (cyclobenzaprine) risks & warnings »
  • Taking other medications that also cause sleepiness
  • Recreational drug use
  • Excessive alcohol use
  • Elderly
  • Prior history of drug abuse
Detailed Soma (carisoprodol) risks & warnings »
Pregnancy
Alcohol
FlexerilSoma
No alcohol related info.
  • Don't drink alcohol while on this medication.
Pain
FlexerilSoma
  • Can relieve pain associated with muscle spasms.
No pain related info.
Sleep
FlexerilSoma
  • Taking Flexeril (cyclobenzaprine) may make you feel dizzy or sleepy for the first few days. Avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.
  • Flexeril (cyclobenzaprine) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
No sleep related info.
Upsides and benefits
FlexerilSoma
  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women, but talk to your doctor about it first.
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
Downsides and risks
FlexerilSoma
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with heart conditions (like rhythm problems, heart failure, or recent heart attack).
  • Can make you have dry mouth.
  • Not effective for muscle spasms caused by brain or spinal injuries.
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
Tips from our pharmacists for people taking the medication
FlexerilSoma
  • Flexeril (cyclobenzaprine) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Flexeril (cyclobenzaprine) is not meant to be used long-term. It should be used for only 2 to 3 weeks maximum.
  • Flexeril (cyclobenzaprine) can cause dry mouth.
  • Take it roughly at the same time every day.
  • If you are using the capsules, you may swallow it whole or sprinkle contents on a tablespoon of applesauce and swallow immediately without chewing.
  • Take the medication at the same time each day.
  • Soma (carisoprodol) is not meant to be used long-term. It should be used for only 2 to 3 weeks maximum.
  • Can cause dizziness, fatigue, and sleepiness.
  • Don't drink alcohol while on this medication.
  • Soma (carisoprodol) can cause stomach pain, nausea and vomiting.
Learn more
More about FlexerilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Flexeril (cyclobenzaprine)?
Worth itNot sureNot worth it
More about SomaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Soma (carisoprodol)?
Worth itNot sureNot worth it