Compare Flexeril vs. Soma

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flexeril
(Cyclobenzaprine)

Soma
(Carisoprodol)

Relaxes your muscles. Flexeril (Cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.Relaxes your muscles. Soma (Carisoprodol) is widely used to treat muscle spasms and is available as a generic, but it's not considered a first-choice treatment for muscle spasms. It's also not meant for long-term therapy.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.69Flexeril
Reviews for Flexeril (Cyclobenzaprine)
66%
of people (All ages) say Flexeril (Cyclobenzaprine) is worth it
37%
say it works well
14%
say it's a big hassle
1064 reviews
Have you used Flexeril (Cyclobenzaprine)?
Worth itNot sureNot worth it
Reviews for Soma (Carisoprodol)
61%
-5% worse vs. Flexeril (Cyclobenzaprine)
39%
+2% better vs. Flexeril (Cyclobenzaprine)
9%
+5% better vs. Flexeril (Cyclobenzaprine)
220 reviews
Have you used Soma (Carisoprodol)?
Worth itNot sureNot worth it
Side effects
FlexerilSoma
  • Dry mouth 4%
  • Dizziness 1%
  • Fatigue 1%
  • Nausea 2%
  • Drowsiness 100%
  • Headache nos 17%
  • Dry throat 8%
  • Acne nos 6%
  • Disturbance in attention 6%
More Flexeril side effects »
  • Drowsiness 7%
  • Dizziness 6%
  • Hedache 3%
  • Central nervous system reactions 2%
More Soma side effects »
How it works
FlexerilSoma
Flexeril (Cyclobenzaprine) is a muscle relaxer. It works in the brain to help calm down muscle spasms without interfering with normal muscle function.Soma (Carisoprodol) is a muscle relaxant. It works in the brain to help calm down muscle spasms.
Type of medication
FlexerilSoma
Prescription only
Prescription only
Available as
FlexerilSoma
  • Pill
  • Extended release
  • Pill
Used for
FlexerilSoma
Risk factors for serious side effects
FlexerilSoma
  • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting
  • Taking other medications for your mood
  • Alcohol or drug use
  • Age over 65
  • Taking tramadol
Detailed Flexeril (Cyclobenzaprine) risks & warnings »
  • Taking other medications that also cause sleepiness
  • Recreational drug use
  • Excessive alcohol use
  • Prior history of drug abuse
  • Prior history of overdoses of drugs of abuse, recreational drugs or alcohol
Detailed Soma (Carisoprodol) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
FlexerilSoma
  • Don't drink alcohol while on this medication.
  • Don't drink alcohol while on this medication.
Pain
FlexerilSoma
  • Can relieve pain associated with muscle spasms.
  • Can cause stomach pain, nausea and vomiting.
Sleep
FlexerilSoma
  • Taking Flexeril (Cyclobenzaprine) may make you feel dizzy or sleepy for the first few days, especially if you drink a lot of alcohol or take recreational drugs. Your body should adjust to this, however, avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.
No sleep related info.
Upsides and benefits
FlexerilSoma
  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women.
  • Available in generic.
  • Available in two different strengths, although the smaller strength is only available as brand name and thus more expensive.
Downsides and risks
FlexerilSoma
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with recent heart issues (like rhythm problems, heart failure, or heart attack).
  • Not first line for treating muscle spasms.
  • Can cause dizziness and sleepiness.
  • Not meant for long term therapy.
  • Can cause dependence and withdrawal symptoms if you stop taking it suddenly.
Tips from our pharmacists for people taking the medication
FlexerilSoma
  • Can cause dizziness, fatigue, and sleepiness.
  • Take the medication at the same time each day.
  • Not to be used for long-term treatment.
  • Don't drink alcohol while on this medication.
  • Can cause dizziness, fatigue, and sleepiness.
  • Take the medication at the same time each day.
  • Not to be used for long-term treatment (2 to 3 weeks maximum)
  • Don't drink alcohol while on this medication.
  • Can cause stomach pain, nausea and vomiting.
Learn more
More about FlexerilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Flexeril (Cyclobenzaprine)?
Worth itNot sureNot worth it
More about SomaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Soma (Carisoprodol)?
Worth itNot sureNot worth it