Compare Flexeril vs. Valium

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flexeril
(cyclobenzaprine)

Valium
(diazepam)

Relaxes your muscles. Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.Helps you relax. Valium (Diazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety and for pain and sleeplessness from muscle spasm. Less severe withdrawal symptoms compared to similar drugs.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Valium
Best available price for 60 (5mg) tablets of valium
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.69Flexeril
Reviews for Flexeril
66%
of people (All ages) say Flexeril is worth it
37%
say it works well
14%
say it's a big hassle
1064 reviews
Have you used Flexeril (cyclobenzaprine)?
Worth itNot sureNot worth it
Reviews for Valium
70%
-4% worse vs. Flexeril
53%
-16% worse vs. Flexeril
15%
+1% better vs. Flexeril
976 reviews
Have you used Valium (diazepam)?
Worth itNot sureNot worth it
Side effects
FlexerilValium
  • Dry mouth 4%
  • Dizziness 1%
  • Fatigue 1%
  • Nausea 2%
  • Sleepiness 100%
  • Headache 17%
  • Dry throat 8%
  • Acne 6%
  • Disturbance in attention 6%
  • Drowsiness 18%
More Flexeril side effects »

The Valium FDA package insert doesn’t have numbers about how common side effects are.

More about Valium side effects »
How it works
FlexerilValium
Flexeril (cyclobenzaprine) is a muscle relaxer. It works in the brain to help calm down muscle spasms without interfering with normal muscle function.Valium (Diazepam) is a fast-acting benzodiazepine. It affects neurotransmitters in the brain and calms the nervous system. This reduces anxiety and muscle spasms, and causes sleepiness.
Type of medication
FlexerilValium
Prescription onlyPrescription only
Available as
FlexerilValium
  • Pill
  • Liquid
  • Pill
  • Liquid
  • Rectal gel
Used for
FlexerilValium
Risk factors for serious side effects
FlexerilValium
  • Taking monoamine oxidase inhibitors (MAOI)
  • Taking other medications for your mood
  • Alcohol or drug use
  • Age over 65 years
  • Recent heart attack
Detailed Flexeril (cyclobenzaprine) risks & warnings »
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Alcohol
Detailed Valium (diazepam) risks & warnings »
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
FlexerilValium
No alcohol related info.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
Kidneys and liver
FlexerilValium
No kidneys and liver related info.
  • Processed by the liver, so might not be the best choice if you have liver problems.
Pain
FlexerilValium
  • Can relieve pain associated with muscle spasms.
No pain related info.
Sleep
FlexerilValium
  • Taking Flexeril (cyclobenzaprine) may make you feel dizzy or sleepy for the first few days. Avoid driving or other activities requiring concentration until you know how your body responds to the medication. Talk to your doctor or pharmacist if these symptoms bother you.
  • Flexeril (cyclobenzaprine) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
Upsides and benefits
FlexerilValium
  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women, but talk to your doctor about it first.
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Effective at relieving muscle spasms caused by a variety of conditions.
  • Less severe withdrawal symptoms compared to other benzodiazepines.
Downsides and risks
FlexerilValium
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with heart conditions (like rhythm problems, heart failure, or recent heart attack).
  • Can make you have dry mouth.
  • Not effective for muscle spasms caused by brain or spinal injuries.
  • Processed by the liver, so might not be the best choice if you have liver problems.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Most people find that it gets less effective over time.
Tips from our pharmacists for people taking the medication
FlexerilValium
  • Flexeril (cyclobenzaprine) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Flexeril (cyclobenzaprine) is not meant to be used long-term. It should be used for only 2 to 3 weeks maximum.
  • Flexeril (cyclobenzaprine) can cause dry mouth.
  • Take it roughly at the same time every day.
  • If you are using the capsules, you may swallow it whole or sprinkle contents on a tablespoon of applesauce and swallow immediately without chewing.
  • Good for short-term relief of anxiety symptoms.
  • Starts working in 30 minutes when swallowed.
  • Helpful with muscle spasms.
  • Can cause temporary dizziness and drowsiness.
  • Addictive. Long-term use can cause dependence or abuse.
  • Not safe to use with alcohol.
Learn more
More about FlexerilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Flexeril (cyclobenzaprine)?
Worth itNot sureNot worth it
More about ValiumSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Valium (diazepam)?
Worth itNot sureNot worth it