Compare Flexeril vs. Valium

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flexeril (cyclobenzaprine)

Prescription only

Valium (diazepam)

Prescription only
Relaxes your muscles.

Flexeril (cyclobenzaprine) is widely used to treat muscle spasms and is available as a generic, but it shouldn't be used long-term.

4.7/ 7 average rating with 1064 reviewsforFlexeril
Helps you relax.

Valium (diazepam) is effective for occasional or short-term use for anxiety and muscle spasm. Compared to similar drugs, Valium (diazepam) acts very quickly but can have interactions with other medicines.

5.2/ 7 average rating with 976 reviewsforValium
Upsides
  • Can relieve pain associated with muscle spasms.
  • Available as a generic medication.
  • Can be used by pregnant women, but talk to your doctor about it first.
  • Valium (diazepam) effectively relieves anxiety and muscle spasms.
  • Valium (diazepam) has less severe withdrawal symptoms compared to other similar drugs.
  • Works very quickly.
  • Available in generic.
Downsides
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy.
  • Not recommended in elderly patients, people with glaucoma, or in people with heart conditions (like rhythm problems, heart failure, or recent heart attack).
  • Can make you have dry mouth.
  • Not effective for muscle spasms caused by brain or spinal injuries.
  • Use of Valium (diazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Valium (diazepam) can be habit-forming, so it's not typically used for long-term treatment.
  • Most people find that their body will get used to Valium (diazepam) levels and they may need higher doses over time to achieve the same effect.
  • People with severe liver problems should not take Valium (diazepam). Several drugs can also interfere with how Valium (diazepam) works.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
Price
Lowest price near you
$8.1
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$6.58
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Reviews
1064 
66%
think this treatment is worth it
37%
think this treatment works well
14%
think this treatment is a hassle

Have you used Flexeril (cyclobenzaprine)?

Leave a review
976 
70%
think this treatment is worth it
53%
think this treatment works well
15%
think this treatment is a hassle

Have you used Valium (diazepam)?

Leave a review
Side effects
4possible side effects
  • Dry mouth
    6%
  • Dizziness
    3%
  • Fatigue
    3%
  • Nausea
    3%
See more detailed side effects
The Valium (diazepam) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Serotonin syndrome

    Taking monoamine oxidase inhibitors (MAOI)

    ...and 1 more risk factors

  • Dizziness and sleepiness

    Alcohol or drug use

    ...and 1 more risk factors

  • Heart attack or stroke

    Recent heart attack

    ...and 2 more risk factors

  • Dehydration

    Older than 65 years

    ...and 1 more risk factors

  • Overactive Thyroid

    Overactive thyroid

See more detailed risks and warnings
  • Decreased breathing from use with opioids

    Taking Valium (diazepam) with opioids, drugs or alcohol

    ...and 1 more risk factors

  • Dependence and withdrawal

    History of substance abuse

    ...and 4 more risk factors

  • Driving impairment

    Alcohol use with Valium (diazepam)

    ...and 1 more risk factors

  • Drug interactions

    Current liver problems

    ...and 1 more risk factors

See more detailed risks and warnings