Compare Flonase vs. Allegra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Flonase (Fluticasone)

Prescription or OTC

Allegra (fexofenadine)

Over-the-counter
Relieves allergy symptoms.

Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.

3.7/ 5 average rating with 890 reviewsforFlonase
Treats allergy symptoms.

Allegra (fexofenadine) relieves allergy symptoms without making you feel drowsy.

3.9/ 5 average rating with 24 reviewsforAllegra
Upsides
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic medication.
  • Allegra (fexofenadine) is effective at reducing symptoms for seasonal allergies and chronic hives without significant drowsiness, unlike Benadryl.
  • Approved for kids aged 6 months or older.
  • Allegra (fexofenadine) comes in many forms, like tablet, liquid, and quick-dissolving tablet.
Downsides
  • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
  • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
  • Allegra (fexofenadine)'s effectiveness can wear off over time.
  • The dose needs to be adjusted for people with kidney problems.
Used for
Dosage forms
  • Nasal spray
  • Pill
  • Dissolving tablet
  • Liquid
Price
No pricing information available
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Reviews
890 reviews so far
72%
saidit'sworth it
43%
saiditworked well
7%
saidit'sa big hassle

Have you used Flonase (Fluticasone)?

Leave a review
24 reviews so far
79%
saidit'sworth it
63%
saiditworked well
0%
saidit'sa big hassle

Have you used Allegra (fexofenadine)?

Leave a review
Side effects
The Flonase (Fluticasone) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Dizziness
    2%
  • Back Pain
    2%
  • Stomach discomfort
    2%
  • Pain in hands/feet
    2%
See more detailed side effects
Risks and risk factors
  • Adrenal suppression
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Flonase (Fluticasone)
  • Allergic reactions
  • Decrease in growth in children and teenagers
    • Long-term use
    • Taking more than recommended dose
  • Adrenal suppression
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Flonase (Fluticasone)
  • Thrush in the nose and throat
    • Long-term use
  • Reduced immune system
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
  • Decreased wound healing
    • Surgery or trauma to the nose or sinuses
  • Changes in the nasal septum
    • Long-term use
See more detailed risks and warnings
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Brain damage from too much phenylalanine
    • History of phenylketonuria (PKU)
See more detailed risks and warnings