Compare Flonase vs. Nasonex

Flonase (Fluticasone) and Nasonex (Mometasone) are steroids that help relieve allergy symptoms, and are both available as nasal spray. Flonase is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives. Nasonex is also a good first-choice treatment but can take 1 to 2 weeks to start working fully.

Flonase
(Fluticasone)

Nasonex
(Mometasone)

Relieves allergy symptoms. Flonase (Fluticasone) is a good first-choice medicine for treating a runny or stuffy nose caused by allergies, and it's cheaper than some alternatives.Relieves allergy symptoms. Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
No pricing data for this drug at this filter setting. Try searching onGoodRx
Reviews & ratings
Button Group. All currently active
Button Group. All currently active
5.048808172531214Flonase
Reviews for Flonase (Fluticasone)
72%
of people say Flonase (Fluticasone) is worth it
43%
say it works well
7%
say it's a big hassle
Reviews for Nasonex (Mometasone)
68%
4% vs. Flonase (Fluticasone)
38%
5% vs. Flonase (Fluticasone)
8%
1% vs. Flonase (Fluticasone)
Side effects
FlonaseNasonex
  • Asthma symptoms 4%
  • Nausea/vomiting 3%
  • Nosebleed 2%
  • Headache 1%
  • Cough 1%
  • Sore throat 1%
More Flonase side effects »
  • Nosebleed 8%
  • Headache 4%
  • Viral infection 3%
  • Menstrual cramps 2%
  • Sinus inflammation 2%
  • Musculoskeletal pain 2%
  • Sore throat 2%
  • Coughing 1%
  • Vomiting 1%
More Nasonex side effects »
How it works
FlonaseNasonex
Flonase (Fluticasone) is a nasal steroid. It works directly in your nose to reduce swelling and inflammation caused by allergies.Nasonex (Mometasone) is a topical steroid. It works directly where it's applied to help reduce swelling and inflammation in your nose.
Type of medication
FlonaseNasonex
Anti-inflammatory
Corticosteroid
Prescription or OTC
Anti-inflammatory
Corticosteroid
Prescription only
Available as
FlonaseNasonex
  • Nasal spray
  • Nasal spray
Used for (click to learn more)
FlonaseNasonex
Risk factors for serious side effects
FlonaseNasonex
  • Switching from oral or injectable steroids to inhaled, especially if used long term
  • Using other inhaled steroids with Flonase (Fluticasone)
    • Long-term use
    • Taking more than recommended dose
    • Switching from oral or injectable steroids to inhaled, especially if used long term
    • Using other inhaled steroids with Flonase (Fluticasone)
    • Long-term use
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
    • Surgery or trauma to the nose or sinuses
    • Long-term use
    Detailed Flonase (Fluticasone) risks & warnings »
    • Long-term use
    • Long-term use
    • Surgery or trauma to the nose or sinuses
    • Long-term use
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
    • Long-term use
    • Taking more than recommended dose
    Detailed Nasonex (Mometasone) risks & warnings »
    Pregnancy category
    FlonaseNasonex
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    FlonaseNasonex
    • Available as a generic medication.
    • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
    • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
    • Can be used as needed to help control symptoms in people age 13 years or older.
    • Available as a generic, which is cheaper.
    • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
    • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
    • Can be used as needed to help control symptoms in people age 13 years or older.
    Downsides and risks
    FlonaseNasonex
    • Flonase (Fluticasone) doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
    • Needs to be primed (pressed/pumped until a fine spray appears) up to six times prior to using it for the first time, or if you haven't used it in 2 weeks.
    • Since the medicine in Flonase (Fluticasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
    • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
    • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
    • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
    Tips from our pharmacists for people taking the medication
    FlonaseNasonex
    • It can take several days for Flonase (Fluticasone) to start working fully.
    • Don't take more of it than was prescribed for you.
    • Blow your nose before using Flonase (Fluticasone).
    • Can cause thrush (a fungal infection) inside the nose and throat.
    • Can also cause a headache, sore throat, or nosebleeds.
    • Use Nasonex (Mometasone) once a day, following age-specific recommendations on how many sprays to use. Don't take more than prescribed.
    • Blow your nose before using.
    • Can cause thrush (a fungal infection) inside your nose and throat. Can also cause nosebleeds, a sore throat, and headaches.
    • Needs to be used regularly during allergy season for it to work. It can take 1 to 2 weeks for the medicine to start working fully.
    • Check with your doctor or pharmacist on how to use the nasal spray the right way.
    • Shake well before using it. Before the first use, prime the bottle by spraying it until you see a fine mist.
    Learn more
    More about FlonaseSide effectsReviews & ratingsAlternativesFDA package insert
    More about NasonexSide effectsReviews & ratingsAlternativesFDA package insert