Compare Fluoxymesterone vs. Androderm

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Androxy
(Fluoxymesterone)

Androderm
(Testosterone Patch)

Treats low testosterone. While Androxy (Fluoxymesterone) is available for treating low testosterone, other treatments are better first choices.Treats low testosterone. The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.
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Reviews & ratings
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Button Group. All currently active
3.742574257425743Fluoxymesterone
Reviews for Androxy (Fluoxymesterone)
47%
of people say Androxy (Fluoxymesterone) is worth it
23%
say it works well
27%
say it's a big hassle

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Side effects
FluoxymesteroneAndroderm

The Fluoxymesterone FDA package insert doesn’t have numbers about how common side effects are.

More about Fluoxymesterone side effects »

The Androderm FDA package insert doesn’t have numbers about how common side effects are.

More about Androderm side effects »
How it works
FluoxymesteroneAndroderm
Androxy (Fluoxymesterone) works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on. Also, it can slow the spread of certain kinds of breast cancer.The testosterone patch works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
FluoxymesteroneAndroderm
Hormone replacementPrescription only
Hormone replacement
Testosterone
Prescription only
Available as
FluoxymesteroneAndroderm
  • Pill
  • Patch
Used for (click to learn more)
FluoxymesteroneAndroderm
  • Low testosterone
  • Low testosterone
Risk factors for serious side effects
FluoxymesteroneAndroderm
  • Diabetes
  • Male
  • Male
  • Enlarged prostate (benign prostatic hypertrophy)
  • Taking high doses of Androxy (Fluoxymesterone)
  • Heart, liver or kidney disease
  • Female
  • Breast cancer
  • Inability to move
      Detailed Androxy (Fluoxymesterone) risks & warnings »
      Coming soon.
      Pregnancy category
      FluoxymesteroneAndroderm
      XFDA pregnancy category (Unsafe)

      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

      See the FDA package insert
      XFDA pregnancy category (Unsafe)

      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      No specific food-related info.No specific food-related info.
      Kidneys and liver
      • There have been reports of people on Androxy (Fluoxymesterone) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This has happened if you have breast cancer or if you are unable to move around. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
      No specific kidneys and liver-related info.
      Sex
      • Can cause increased acne and changes in sex drive.
      • If you're a man taking Androxy (Fluoxymesterone), you can see changes in your sex drive, including overstimulation and prolonged frequent erections. Talk to your doctor if this happens, since they might have to change the dose.
      • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      • If you're taking Androxy (Fluoxymesterone), and you notice swelling in your legs, or a sudden increase in your weight, talk to your doctor. This can be a serious side effect involving your heart.
      No specific weight-related info.
      Upsides and benefits
      FluoxymesteroneAndroderm
      • Available as an oral tablet.
      • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
      • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
      • The testosterone patch only has to be placed once each night.
      Downsides and risks
      FluoxymesteroneAndroderm
      • Not considered a first-choice treatment for low testosterone, and not recommended for treating breast cancers that respond to testosterone.
      • Available only as brand name, so it can be expensive.
      • Not available in generic.
      • You have to be careful to rotate the testosterone patch to a different part of your body each night.
      • Can cause skin irritation.
      • Has to be removed before you have an MRI.
      • The patch can become loose if you do heavy exercise or sweat a lot.
      Tips from our pharmacists for people taking the medication
      FluoxymesteroneAndroderm
      • Can cause nausea, vomiting, and headache.
      • Don't double up if you miss a dose.
      • Can cause increased acne and changes in sex drive.
      • Keep this medication locked up and away from children since it's a controlled substance.
      • Place the testosterone patch on a clean, dry area of your skin each night. Don't put it on your scrotum or a bony part of your body.
      • Change the area where you place the testosterone patch every night, and wait at least 7 days before you put in on the same site again.
      • Make sure the patch is attached to your skin, especially along the edges. If it loosens, smooth the edges and then the center of the patch with your finger to make sure it's attached completely.
      • If the patch falls off before noon, apply another patch. If it falls off after that, don't apply another patch until your regular time at night. Don't use tape to keep the patch attached.
      • Don't bathe or swim for at least 3 hours after you put a new patch on. Also, heavy exercise or lots of sweating can make your patch fall off.
      Learn more
      More about FluoxymesteroneSide effectsReviews & ratingsAlternativesFDA package insert
      More about AndrodermSide effectsReviews & ratingsAlternativesFDA package insert