Compare Fluoxymesterone vs. Androderm

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Androxy
(Fluoxymesterone)

Androderm
(Testosterone Patch)

Treats low testosterone. While Androxy (Fluoxymesterone) is available for treating low testosterone, other treatments are better first choices.Treats low testosterone. The testosterone patch is a topical form of hormone replacement that doesn't affect people you come in contact with, but it can cause skin irritation so you have to rotate its position every night.
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Reviews & ratings
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Have you used Androxy (Fluoxymesterone)?
Worth itNot sureNot worth it

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Have you used Androderm (Testosterone Patch)?
Worth itNot sureNot worth it
Side effects
FluoxymesteroneAndroderm

The Fluoxymesterone FDA package insert doesn’t have numbers about how common side effects are.

More about Fluoxymesterone side effects »
  • Any appication site reaction 28%
  • Application site pruritus 17%
  • Application site vesicles 6%
  • Back pain 6%
  • Application site erythema 3%
  • Application site exfoliation 3%
  • Chills 3%
  • Prostatitis 3%
  • Fatigue 3%
  • Acid reflux disease 3%
More Androderm side effects »
How it works
FluoxymesteroneAndroderm
Androxy (Fluoxymesterone) works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on. Also, it can slow the spread of certain kinds of breast cancer.The testosterone patch works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
FluoxymesteroneAndroderm
Prescription only
Prescription only
Available as
FluoxymesteroneAndroderm
  • Pill
  • Patch
Used for
FluoxymesteroneAndroderm
  • Low Testosterone
  • Low Testosterone
Risk factors for serious side effects
FluoxymesteroneAndroderm
  • Diabetes
  • Male
  • Male
  • Enlarged prostate (benign prostatic hypertrophy)
  • Taking high doses of Androxy (Fluoxymesterone)
  • Heart, liver or kidney disease
  • Female
  • Breast cancer
  • Inability to move
      Detailed Androxy (Fluoxymesterone) risks & warnings »
      Coming soon.
      Pregnancy

      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

      Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

      Kidneys and liver
      FluoxymesteroneAndroderm
      • There have been reports of people on Androxy (Fluoxymesterone) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This has happened if you have breast cancer or if you are unable to move around. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
      No kidneys and liver related info.
      Pain
      FluoxymesteroneAndroderm
      • If you're on Androxy (Fluoxymesterone), and you notice pain in your abdomen, or if your skin or the whites of your eyes turn yellow, call your doctor immediately. This can be liver damage.
      No pain related info.
      Upsides and benefits
      FluoxymesteroneAndroderm
      • Available as an oral tablet.
      • The testosterone patch doesn't have to be removed when you're having sex or if you're showering or bathing.
      • The testosterone patch prevents other people around you from coming in contact with testosterone, unlike other topical forms such as gels.
      • The testosterone patch only has to be placed once each night.
      Downsides and risks
      FluoxymesteroneAndroderm
      • Not considered a first-choice treatment for low testosterone, and not recommended for treating breast cancers that respond to testosterone.
      • Available only as brand name, so it can be expensive.
      • Not available in generic.
      • You have to be careful to rotate the testosterone patch to a different part of your body each night.
      • Can cause skin irritation.
      • Has to be removed before you have an MRI.
      • The patch can become loose if you do heavy exercise or sweat a lot.
      Tips from our pharmacists for people taking the medication
      FluoxymesteroneAndroderm
      • Can cause nausea, vomiting, and headache.
      • Don't double up if you miss a dose.
      • Can cause increased acne and changes in sex drive.
      • Keep this medication locked up and away from children since it's a controlled substance.
      • Place the testosterone patch on a clean, dry area of your skin each night. Don't put it on your scrotum or a bony part of your body.
      • Change the area where you place the testosterone patch every night, and wait at least 7 days before you put in on the same site again.
      • Make sure the patch is attached to your skin, especially along the edges. If it loosens, smooth the edges and then the center of the patch with your finger to make sure it's attached completely.
      • If the patch falls off before noon, apply another patch. If it falls off after that, don't apply another patch until your regular time at night. Don't use tape to keep the patch attached.
      • Don't bathe or swim for at least 3 hours after you put a new patch on. Also, heavy exercise or lots of sweating can make your patch fall off.
      Learn more
      More about FluoxymesteroneSide effectsAlternativesFDA package insert
      Have you used Androxy (Fluoxymesterone)?
      Worth itNot sureNot worth it
      More about AndrodermSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Androderm (Testosterone Patch)?
      Worth itNot sureNot worth it