Compare Fluoxymesterone vs. Axiron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

fluoxymesterone

Axiron
(Testosterone Topical Solution)

Treats low testosterone. While Androxy (Fluoxymesterone) is available for treating low testosterone, other treatments are better first choices.Treats low testosterone. This testosterone topical solution is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.
Reviews & ratings
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Have you used Androxy (Fluoxymesterone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Axiron (Testosterone Topical Solution)?
Worth itNot sureNot worth it
Side effects
FluoxymesteroneAxiron

The Fluoxymesterone FDA package insert doesn’t have numbers about how common side effects are.

More about Fluoxymesterone side effects »
  • Diarrhea 3%
  • Vomiting 3%
  • Hematocrit Increased 4%
  • PSA Increased 4%
  • Application Site Erythema 5%
  • Headache 5%
  • Application Site Irritation 7%
More Axiron side effects »
How it works
FluoxymesteroneAxiron
Androxy (Fluoxymesterone) works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on. Also, it can slow the spread of certain kinds of breast cancer.Testosterone topical solution works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
FluoxymesteroneAxiron
Prescription onlyNo lower cost generic availablePrescription onlyNo lower cost generic available
Available as
FluoxymesteroneAxiron
  • Pill
  • Topical
Used for
FluoxymesteroneAxiron
  • Low Testosterone
  • Low Testosterone
Risk factors for serious side effects
FluoxymesteroneAxiron
  • Diabetes
  • Male
  • Enlarged prostate (benign prostatic hypertrophy)
  • Taking high doses of Androxy (Fluoxymesterone)
Detailed Androxy (Fluoxymesterone) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Kidneys and liver
    FluoxymesteroneAxiron
    • There have been reports of people on Androxy (Fluoxymesterone) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This has happened if you have breast cancer or if you are unable to move around. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
    No kidneys and liver related info.
    Pain
    FluoxymesteroneAxiron
    • If you're on Androxy (Fluoxymesterone), and you notice pain in your abdomen, or if your skin or the whites of your eyes turn yellow, call your doctor immediately. This can be liver damage.
    No pain related info.
    Upsides and benefits
    FluoxymesteroneAxiron
    • Available as an oral tablet.
    • You're less likely with this formulation to transfer testosterone topical solution to another person since this is applied to the armpits -- unlike some other forms of topical testosterone.
    • You can use your regular deodorant or antiperspirant, but just make sure to apply that first before using testosterone topical solution.
    Downsides and risks
    FluoxymesteroneAxiron
    • Not considered a first-choice treatment for low testosterone, and not recommended for treating breast cancers that respond to testosterone.
    • Available only as brand name, so it can be expensive.
    • Only available as brand name.
    • You have to wait at least 2 hours after applying testosterone topical solution before you can swim or bathe, otherwise your body won't absorb the entire amount.
    Tips from our pharmacists for people taking the medication
    FluoxymesteroneAxiron
    • Can cause nausea, vomiting, and headache.
    • Don't double up if you miss a dose.
    • Can cause increased acne and changes in sex drive.
    • Keep this medication locked up and away from children since it's a controlled substance.
    • Prime testosterone topical solution first by pumping 3 times before you use a new bottle.
    • If you use deodorant or antiperspirant, apply that first before using testosterone topical solution.
    • Don't swim or bathe for at least 2 hours after you put on testosterone topical solution so that it has time to absorb.
    • Cover the area with clothing as soon as it's dry so you don't spread it to other people.
    • If you think you'll have skin-to-skin contact at the area where you've placed testosterone topical solution, wash that area with soap and water then dry.
    • Don't use testosterone topical solution anywhere besides your armpits.
    Learn more
    More about FluoxymesteroneSide effectsAlternativesFDA package insert
    Have you used Androxy (Fluoxymesterone)?
    Worth itNot sureNot worth it
    More about AxironSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Axiron (Testosterone Topical Solution)?
    Worth itNot sureNot worth it