Compare Fluoxymesterone vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Androxy
(fluoxymesterone)

Depo-Testosterone
(testosterone cypionate injection)

Treats low testosterone. While Androxy (Fluoxymesterone) is available for treating low testosterone, other treatments are better first choices.Treats low testosterone. This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.
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Coupons for Fluoxymesterone
Best available price for 60 (10mg) tablets of fluoxymesterone
Coupons for Depo-Testosterone
Best available price for 1 (1ml of 200mg/ml) vial of testosterone-cypionate
Reviews & ratings
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Have you used Androxy (fluoxymesterone)?
Worth itNot sureNot worth it
Reviews for Depo-Testosterone
49%
-49% worse vs. Fluoxymesterone
32%
-32% worse vs. Fluoxymesterone
17%
+17% better vs. Fluoxymesterone
100 reviews
Have you used Depo-Testosterone (testosterone cypionate injection)?
Worth itNot sureNot worth it
Side effects
FluoxymesteroneDepo-Testosterone

The Fluoxymesterone FDA package insert doesn’t have numbers about how common side effects are.

More about Fluoxymesterone side effects »

The Depo-Testosterone FDA package insert doesn’t have numbers about how common side effects are.

More about Depo-Testosterone side effects »
How it works
FluoxymesteroneDepo-Testosterone
Androxy (Fluoxymesterone) works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on. Also, it can slow the spread of certain kinds of breast cancer.The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
FluoxymesteroneDepo-Testosterone
Prescription onlyPrescription only
Available as
FluoxymesteroneDepo-Testosterone
  • Pill
  • Injection
Used for
FluoxymesteroneDepo-Testosterone
  • Low Testosterone
  • Low Testosterone
Risk factors for serious side effects
FluoxymesteroneDepo-Testosterone
  • Diabetes
  • Male
  • Enlarged prostate (benign prostatic hypertrophy)
  • Taking high doses of Androxy (Fluoxymesterone)
Detailed Androxy (fluoxymesterone) risks & warnings »
  • Male
  • Enlarged prostate (benign prostatic hypertrophy)
  • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Heart, liver or kidney disease
Detailed Depo-Testosterone (testosterone cypionate injection) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Kidneys and liver
FluoxymesteroneDepo-Testosterone
  • There have been reports of people on Androxy (Fluoxymesterone) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This has happened if you have breast cancer or if you are unable to move around. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
  • There have been reports of people on Depo-Testosterone (Testosterone Cypionate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you are unable to move around or have cancer. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
Pain
FluoxymesteroneDepo-Testosterone
  • If you're on Androxy (Fluoxymesterone), and you notice pain in your abdomen, or if your skin or the whites of your eyes turn yellow, call your doctor immediately. This can be liver damage.
No pain related info.
Upsides and benefits
FluoxymesteroneDepo-Testosterone
  • Available as an oral tablet.
  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
Downsides and risks
FluoxymesteroneDepo-Testosterone
  • Not considered a first-choice treatment for low testosterone, and not recommended for treating breast cancers that respond to testosterone.
  • Available only as brand name, so it can be expensive.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
Tips from our pharmacists for people taking the medication
FluoxymesteroneDepo-Testosterone
  • Can cause nausea, vomiting, and headache.
  • Don't double up if you miss a dose.
  • Can cause increased acne and changes in sex drive.
  • Keep this medication locked up and away from children since it's a controlled substance.
  • Your doctor will show you how to inject this correctly.
  • Can cause nausea, vomiting and headache.
  • Can cause increased acne and changes in sex drive.
  • Keep this medication locked up and away from children since it's a controlled substance.
Learn more
More about FluoxymesteroneSide effectsAlternativesFDA package insert
Have you used Androxy (fluoxymesterone)?
Worth itNot sureNot worth it
More about Depo-TestosteroneSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Depo-Testosterone (testosterone cypionate injection)?
Worth itNot sureNot worth it