Compare fluphenazine vs. fluphenazine decanoate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prolixin
(fluphenazine)

Prolixin Decanoate
(fluphenazine decanoate)

Treats schizophrenia and psychosis. Prolixin (fluphenazine) can stabilize your mood. It is used to find the right dose for you before moving to a long-acting injection.Treats schizophrenia or psychosis. Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.
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Reviews & ratings
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Reviews for Prolixin (fluphenazine)
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of people (All ages) say Prolixin (fluphenazine) is worth it
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say it works well
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say it's a big hassle
Have you used Prolixin (fluphenazine)?
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Reviews for Prolixin Decanoate (fluphenazine decanoate)
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Same vs. Prolixin (fluphenazine)
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Same vs. Prolixin (fluphenazine)
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Same vs. Prolixin (fluphenazine)
Have you used Prolixin Decanoate (fluphenazine decanoate)?
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Side effects
fluphenazinefluphenazine decanoate

The fluphenazine FDA package insert doesn’t have numbers about how common side effects are.

More about fluphenazine side effects »

The fluphenazine decanoate FDA package insert doesn’t have numbers about how common side effects are.

More about fluphenazine decanoate side effects »
How it works
fluphenazinefluphenazine decanoate
Prolixin (fluphenazine) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.Prolixin Decanoate (fluphenazine decanoate) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.
Type of medication
fluphenazinefluphenazine decanoate
Prescription only
Prescription only
Available as
fluphenazinefluphenazine decanoate
  • Pill
  • Liquid
  • Injection
  • Injection
Used for
fluphenazinefluphenazine decanoate
Risk factors for serious side effects
fluphenazinefluphenazine decanoate
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
Detailed Prolixin (fluphenazine) risks & warnings »
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
Detailed Prolixin Decanoate (fluphenazine decanoate) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
fluphenazinefluphenazine decanoate
  • Don't combine with alcohol or narcotics since it can stop your breathing.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
Sleep
fluphenazinefluphenazine decanoate
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Upsides and benefits
fluphenazinefluphenazine decanoate
  • Good at stabilizing your mood.
  • Available in several oral and injectable forms, including a long-acting injection that is taken less frequently.
  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
Downsides and risks
fluphenazinefluphenazine decanoate
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can make it difficult for you to control your movements if you've been on Prolixin (fluphenazine) for a while.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
Tips from our pharmacists for people taking the medication
fluphenazinefluphenazine decanoate
  • Can make you more sensitive to the sun. Wear sunscreen or protective clothing while outside.
  • Can make it difficult for you to start and stop your movements. Talk to your doctor right away if this happens.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
  • Don't stop taking Prolixin (fluphenazine) suddenly. It can be dangerous.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
  • Mix the concentrated form with at least 1/4 cup of fluids. Don't mix with caffeine, tea, or apple juice since it affects the absorption of Prolixin (fluphenazine).
  • Can make you more sensitive to the sun, so wear sunscreen or protective clothing while outside.
  • Can affect how your body regulates your temperature, so drink plenty of liquids especially when you're exercising.
  • Can make it difficult for you to start and stop your movements. Talk to your doctor right away if this happens.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Learn more
More about fluphenazineSide effectsAlternativesFDA package insert
Have you used Prolixin (fluphenazine)?
Worth itNot sureNot worth it
More about fluphenazine decanoateSide effectsAlternativesFDA package insert
Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it