Compare Fortesta vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Fortesta (Testosterone Gel)

Prescription only
Treats low testosterone.

This testosterone gel is a convenient topical form of hormone replacement that's less likely to rub off on other people you come into contact with, but it's not available as a generic yet.

Treats low testosterone.

This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.

4.1/ 7 average rating with 100 reviewsforDepo-Testosterone
Upsides
  • You apply it to your thighs like a lotion.
  • Putting testosterone gel on your thights makes it less likely you'll transfer the medication to other people around you, compared to some other kinds of topical testosterone.
  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
Downsides
  • Not available in generic form, so it can be more expensive.
  • You have to wait at least 2 hours after applying testosterone gel before you can swim or bathe, otherwise your body won't absorb the full amount of the medication.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
Used for
  • Low testosterone
  • Low testosterone
Dosage forms
  • Cream, gel, or ointment
  • Injection
Price
Lowest price near you
$432.04
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Lowest price near you
$28.2
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Reviews
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100 
49%
think this treatment is worth it
32%
think this treatment works well
17%
think this treatment is a hassle

Have you used Depo-Testosterone (Testosterone Cypionate Injection)?

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Side effects
1possible side effects
  • Skin reaction
    16%
See more detailed side effects
The Depo-Testosterone (Testosterone Cypionate Injection) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
No information currently available
  • Breast tissue changes

    Male

  • Changes in sex drive

    Male

  • Inability to urinate

    Enlarged prostate (benign prostatic hypertrophy)

  • Changes in sperm

    Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)

  • Swelling in the legs

    Heart, liver or kidney disease

  • High calcium in the blood

    Inability to move

    ...and 1 more risk factors

  • Changes in blood sugar

    Diabetes

  • Changes in blood thinning

    On blood thinners

See more detailed risks and warnings