Prevents bone loss. Fosamax (Alendronate) is a first-choice treatment for osteoporosis and is available as a generic, but taking it can be a hassle. Prevents bone loss and lowers your risk of breast cancer. Evista (Raloxifene) is effective at reducing bone loss and lowering the risk of breast cancer in postmenopausal women, but does carry the risk of blood clots. How it works Fosamax (Alendronate) is a bisphosphonate. It slows down osteoclasts, the cells that break down bone. This results in greater bone mass and lowers the possibility of fractures. Evista (Raloxifene) is a selective estrogen receptor modulator (SERM). It acts like estrogen to make your bones stronger and less likely to break, and also protects breast and uterus tissues from other estrogen effects. Type of medication Bisphosphonate Prescription only Osteoporosis
› Selective estrogen receptor modulator
Prescription only Available as Pill Effervescent tablet Liquid Used for (click to learn more) Find lowest prices Save on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance. Reviews & ratings Everyone Men Women Button Group. All currently active Everyone Men Women All ages 18-34 35-54 55+ Button Group. All currently active All ages 18-34 35-54 55+ 4.291666666666667 Fosamax
Reviews for Fosamax (Alendronate)
of people say Fosamax (Alendronate) is worth it
say it works well
say it's a big hassle
We haven’t found good data for Fosamax side effects.
FDA side effect reports for Fosamax » More Evista side effects » Risk factors for serious side effects › Oral or dental surgery › Cancer › Poor oral hygiene Detailed Fosamax (Alendronate) risks & warnings » › History of stroke › Heart and blood vessel problems › History of mini stroke (TIA) › Atrial fibrillation › Smoking › High blood pressure › History of high triglycerides Detailed Evista (Raloxifene) risks & warnings » Pregnancy category C FDA pregnancy category (Weigh risks vs. benefits)
Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.
See the FDA package insert X FDA pregnancy category (Unsafe)
Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.
See the FDA package insert
Alcohol No specific alcohol-related info. › Regular exercise, cutting back on smoking, and drinking less alcohol can also reduce your risk of bone loss.
Food No specific food-related info. › Take 1 tablet daily with or without food about the same time each day. It’s important to read the information you get with your medicine about how to take Evista (Raloxifene).
Kidneys and liver No specific kidneys and liver-related info. › Evista (Raloxifene) is processed by the kidney and liver. If you have kidney or liver problems, talk to your doctor because you may need a different dose.
Sex No specific sex-related info. No specific sex-related info.
Sleep No specific sleep-related info. No specific sleep-related info.
Weight No specific weight-related info. No specific weight-related info. Upsides and benefits › Lowers your risk of bone fractures. › Available as a generic medication. › Available in two forms: one that can be taken once a day or another that's taken once a week. › Comes as a regular tablet, an oral solution, or effervescent tablets meant to be dissolved in water. › Evista (Raloxifene) doesn’t affect the breast or uterus the same way that estrogen does, so the risk of cancer is much lower. › Taking Evista (Raloxifene) with calcium and vitamin D improves spine and hip bone health and lowers the risk of fractures. › Lowers total cholesterol and low-density lipoprotein (LDL) cholesterol (the bad cholesterol). Downsides and risks › You need to take it the first thing in the morning with a full glass of water. › Not good for people who can't sit or stand upright for at least 30 minutes in the morning. › The use of bisphosphonates increases your risk of other types of fractures not related to osteoporosis (called atypical fractures). › Can cause bad heartburn or stomach problems. › Can only take Evista (Raloxifene) once you’re in menopause. You can't take it if you're pregnant or breastfeeding. › Evista (Raloxifene) isn’t as effective as tamoxifen at lowering the risk of invasive breast cancer. › Shouldn’t take it with any other forms of estrogen (pills, patches, or injection). › It doesn’t increase bone strength as much as estrogen does and isn’t effective for treating hot flashes. Tips from our pharmacists for people taking the medication › Take Fosamax (Alendronate) first thing in the morning with a full glass of water before eating or drinking anything else, including other medicines. › The pill must be swallowed whole. › Stay upright for at least 30 minutes after taking the medicine, and don't eat or drink anything except plain water during that time. › Make sure you take enough calcium and vitamin D to allow this medicine to work. › Can cause an upset stomach, joint pain, back pain, or heartburn. › Stop taking the medicine and let your doctor know if swallowing becomes painful, if you have chest pain, or if any of the side effects worsen. › If you have dental work coming up, get it done before starting this medicine since some people have experienced serious jaw problems while on Fosamax (Alendronate). › Take 1 tablet daily with or without food about the same time each day. It’s important to read the information you get with your medicine about how to take Evista (Raloxifene). › Your doctor may tell you to take calcium and vitamin D with Evista (Raloxifene) to prevent osteoporosis (bone thinning and loss), especially if you don’t get enough in your diet. › Regular exercise, cutting back on smoking, and drinking less alcohol can also reduce your risk of bone loss. Learn more More about Fosamax Side effects Reviews & ratings Alternatives FDA package insert More about Evista Side effects Reviews & ratings Alternatives FDA package insert