Compare Frova vs. Cafergot

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Frova
(frovatriptan)

Cafergot
(ergotamine / caffeine)

Treats migraine headaches. Triptans are the first-choice to treat migraines. Frova (frovatriptan) works just as well as other triptans for migraines, but doesn't work for other types of headaches like cluster headaches.Treats migraine headaches. Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.
Reviews & ratings
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Have you used Frova (frovatriptan)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Cafergot (ergotamine / caffeine)?
Worth itNot sureNot worth it
Side effects
FrovaCafergot
  • Dizziness 3%
  • Fatigue 3%
  • Headache 1%
  • Tingling or prickling sensation 2%
  • Flushing 2%
  • Dry mouth 2%
  • Hot or cold sensation 1%
  • Muscle pain 1%
  • Indigestion 1%
  • Chest pain 1%
More Frova side effects »

The Cafergot FDA package insert doesn’t have numbers about how common side effects are.

More about Cafergot side effects »
How it works
FrovaCafergot
Frova (frovatriptan) is a triptan. It prevents the opening of blood vessels in your brain, which causes migraines.Cafergot (ergotamine / caffeine) is a combination of ergotamine and caffeine. It tightens the blood vessels in your brain to relieve the pain of your headaches.
Type of medication
FrovaCafergot
Prescription onlyPrescription only
Available as
FrovaCafergot
  • Pill
  • Pill
  • Suppository
Used for
FrovaCafergot
Risk factors for serious side effects
FrovaCafergot
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Frova (frovatriptan) for more than 2 to 3 days a week or 10 days a month
Detailed Frova (frovatriptan) risks & warnings »
  • Overdosing Cafergot (ergotamine / caffeine)
  • Taking triptans (Imitrex, Axert, Maxalt, Amerge, Frova) for migraines
  • Taking Cafergot (ergotamine / caffeine) regularly for months
Detailed Cafergot (ergotamine / caffeine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Sleep
FrovaCafergot
  • Frova (frovatriptan) can make you dizzy or sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
No sleep related info.
Upsides and benefits
FrovaCafergot
  • Frova (frovatriptan) is available in generic.
  • Unlike other similar medicines, you can take up to 3 tablets of Frova (frovatriptan) every 24 hours.
  • Frova (frovatriptan) is first choice of medicines for treatment of migraine headaches.
  • Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
Downsides and risks
FrovaCafergot
  • Available as an oral tablet only, which may be difficult to swallow during bad migraine attack.
  • Doesn't prevent migraines.
  • Doesn't work for other types of headaches like cluster headaches.
  • Not recommended for children under 18 years old.
  • Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
  • Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
  • Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
Tips from our pharmacists for people taking the medication
FrovaCafergot
  • Doesn't prevent migraines.
  • Use as soon as you feel a migraine starting. You can take another dose 2 hours later, but don't take more than 3 tablets in 24 hours.
  • Don't use it excessively since it can cause you to have more headaches. Talk to your doctor if you are having more than 4 migraines in a month.
  • Frova (frovatriptan) can make you dizzy or sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
  • Frova (frovatriptan) can cause nausea or tightness in the chest or throat. Talk to your doctor if it bothers you.
  • Take Cafergot (ergotamine / caffeine) as soon as you feel the migraine coming on.
  • You might be more sensitive to cold when you take Cafergot (ergotamine / caffeine) since it slows down the circulation of your blood in your skin, fingers and toes. Dress warmly.
  • If you have to take more than 6 tablets or 2 suppositories a day or 10 tablets or 5 suppositories in a week of Cafergot (ergotamine / caffeine), talk to your doctor.
  • Don't smoke tobacco if you're taking Cafergot (ergotamine / caffeine).
  • Keep the suppository of Cafergot (ergotamine / caffeine) in the fridge.
Learn more
More about FrovaSide effectsAlternativesFDA package insert
Have you used Frova (frovatriptan)?
Worth itNot sureNot worth it
More about CafergotSide effectsAlternativesFDA package insert
Have you used Cafergot (ergotamine / caffeine)?
Worth itNot sureNot worth it