Compare Frova vs. Imitrex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Frova
(frovatriptan)

Imitrex
(sumatriptan)

Treats migraine headaches. Triptans are the first-choice to treat migraines. Frova (frovatriptan) works just as well as other triptans for migraines, but doesn't work for other types of headaches like cluster headaches.Treats migraine headaches. Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.
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Prices and coupon for 1 (9 tablets of 2.5mg) dose pack of frovatriptan
Coupons for
Prices and coupon for 1 (9 tablets of 100mg) dose pack of sumatriptan
Reviews & ratings
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Have you used Frova (frovatriptan)?
Worth itNot sureNot worth it
Reviews for Imitrex (sumatriptan)
74%
+74% better vs. Frova (frovatriptan)
68%
+68% better vs. Frova (frovatriptan)
19%
-19% worse vs. Frova (frovatriptan)
Have you used Imitrex (sumatriptan)?
Worth itNot sureNot worth it
Side effects
FrovaImitrex
  • Dizziness 3%
  • Fatigue 3%
  • Headache 1%
  • Tingling or prickling sensation 2%
  • Flushing 2%
  • Dry mouth 2%
  • Hot or cold sensation 1%
  • Muscle pain 1%
  • Indigestion 1%
  • Chest pain 1%
More Frova side effects »
  • Pain and other pressure sensations 2%
  • Atypical sensations 1%
  • Paresthesia (all types) 1%
  • Sensation warm/cold 1%
  • Pain - location specified 1%
  • Malaise/fatigue 2%
  • Chest - pain/tightness/pressure and/or heaviness 1%
  • Neck/throat/jaw - pain/ tightness/pressure 2%
  • Other - pressure/tightness/ heaviness 1%
  • Vertigo 2%
More Imitrex side effects »
How it works
FrovaImitrex
Frova (frovatriptan) is a triptan. It prevents the opening of blood vessels in your brain, which causes migraines.Imitrex (Sumatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.
Type of medication
FrovaImitrex
Prescription only
Prescription only
Available as
FrovaImitrex
  • Pill
  • Pill
  • Injection
  • Nasal spray
Used for
FrovaImitrex
Risk factors for serious side effects
FrovaImitrex
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Frova (frovatriptan) for more than 2 to 3 days a week or 10 days a month
  • Tricyclic antidepressants
  • Fentanyl
  • Tramadol
  • Buspirone
  • ADHD medicines
  • Triptans
  • Uncontrolled high blood pressure
  • High blood pressure
  • history of stroke or heart attack
Detailed Frova (frovatriptan) risks & warnings »
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Being overweight or obese
  • Smoking
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Being overweight or obese
  • Smoking
    • Patients taking SSRIs and SNRIs
    • History of high blood pressure
    • History of seizures
    Detailed Imitrex (sumatriptan) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Sleep
    FrovaImitrex
    • Frova (frovatriptan) can make you dizzy or sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
    Upsides and benefits
    FrovaImitrex
    • Frova (frovatriptan) is available in generic.
    • Unlike other similar medicines, you can take up to 3 tablets of Frova (frovatriptan) every 24 hours.
    • Frova (frovatriptan) is first choice of medicines for treatment of migraine headaches.
    • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
    • A combination of forms can be used if symptoms do not improve.
    • The nasal spray and injectable forms work very quickly.
    • It's generally safe to use if you are pregnant.
    • Comes in a generic form, so it can be pretty cheap.
    Downsides and risks
    FrovaImitrex
    • Available as an oral tablet only, which may be difficult to swallow during bad migraine attack.
    • Doesn't prevent migraines.
    • Doesn't work for other types of headaches like cluster headaches.
    • Not recommended for children under 18 years old.
    • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
    • Does not prevent migraine headaches; it only treats them once they start.
    • Must wait 1 hour before using second injection.
    • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
    • Need to have your blood pressure checked often, especially if you're pregnant.
    Tips from our pharmacists for people taking the medication
    FrovaImitrex
    • Doesn't prevent migraines.
    • Use as soon as you feel a migraine starting. You can take another dose 2 hours later, but don't take more than 3 tablets in 24 hours.
    • Don't use it excessively since it can cause you to have more headaches. Talk to your doctor if you are having more than 4 migraines in a month.
    • Frova (frovatriptan) can make you dizzy or sleepy. Don't drive or do anything that requires concentration until you know how your body reacts to it.
    • Frova (frovatriptan) can cause nausea or tightness in the chest or throat. Talk to your doctor if it bothers you.
    • Take it as soon as your headache starts.
    • If you use the nasal spray, be sure to blow your nose before using it.
    • If you use the patch, put it on a dry area free of scars, tattoos, or other cuts and scrapes. Be sure to press the button to activate it.
    • If you use the injection, you can use a second injection if you still have a headache after an hour. If you have symptoms 2 hours after the injection, switch to the pill version.
    • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
    • Lie down in a dark room after taking Imitrex (Sumatriptan) to help ease the pain.
    Learn more
    More about FrovaSide effectsAlternativesFDA package insert
    Have you used Frova (frovatriptan)?
    Worth itNot sureNot worth it
    More about ImitrexSide effectsReviews & ratingsFDA package insert
    Have you used Imitrex (sumatriptan)?
    Worth itNot sureNot worth it