Compare Genvoya vs. Descovy

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)

Prescription only
Treats HIV infection.

Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication. It's one of the first choices used to treat HIV infections and contains a newer medication that's safer for your kidneys and bones.

Works with other medicines to treat HIV.

Descovy (emtricitabine / tenofovir alafenamide) is a first choice combination tablet that is used with other medications to treat HIV and is safe for your kidneys and bones.

Upsides
  • First-choice treatment for HIV infections.
  • One tablet contains four different HIV medications and is only taken once daily.
  • Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) has fewer side effects (headache, nausea, fatigue, diarrhea), and is safer on your kidneys and bones than Stribild.
  • Compared to Truvada (a similar drug formulation), Descovy (emtricitabine / tenofovir alafenamide) is safe for your kidneys and bones.
  • Take only once daily, with or without food.
  • Children 12 years or older can take Descovy (emtricitabine / tenofovir alafenamide).
Downsides
  • Should be taken with food.
  • Can increase cholesterol levels.
  • Can interact with many other drugs.
  • Might worsen hepatitis B infections if you suddenly stop taking Descovy (emtricitabine / tenofovir alafenamide).
  • Descovy (emtricitabine / tenofovir alafenamide) is only approved to treat HIV, not to stop you from getting it.
  • Since Descovy (emtricitabine / tenofovir alafenamide) is not a generic, it may be expensive.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$2819.78
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Lowest price near you
$1612.02
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Reviews
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Side effects
4possible side effects
  • Nausea
    10%
  • Diarrhea
    7%
  • Headache
    6%
  • Fatigue
    5%
See more detailed side effects
1possible side effects
  • Nausea
    10%
See more detailed side effects
Risks and warnings
  • Lactic acidosis | Enlarged, fatty liver

    Liver disease

    ...and 2 more risk factors

  • Worsening hepatitis B infection

    Hepatitis B Virus infection

  • Kidney damage

    History of kidney damage

    ...and 1 more risk factors

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

  • Drug interactions

    Taking medicines that interact with Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)

See more detailed risks and warnings
  • Sudden worsening of Hepatitis B virus (HBV)

    Hepatitis B virus

  • Lactic acidosis and enlarged, fatty liver

    Liver disease

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 1 more risk factors

  • Weakened bones

    History of bone fractures

    ...and 1 more risk factors

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

See more detailed risks and warnings