Compare Geodon vs. fluphenazine decanoate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Geodon
(ziprasidone)

Prolixin Decanoate
(fluphenazine decanoate)

Helps control your thoughts and mood. Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.Treats schizophrenia or psychosis. Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Geodon
Best available price for 30 (40mg) capsules of geodon
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.61Geodon
Reviews for Geodon
43%
of people (All ages) say Geodon is worth it
43%
say it works well
30%
say it's a big hassle
Have you used Geodon (ziprasidone)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it
Side effects
Geodonfluphenazine decanoate
  • Extrapyramidal symptoms 6%
  • Drowsiness 7%
  • Nausea 3%
  • Constipation 1%
  • Respiratory tract infection 5%
  • Dizziness 2%
  • Indigestion 1%
  • Restlessness 1%
  • Muscle weakness 2%
  • Diarrhea 1%
More Geodon side effects »

The fluphenazine decanoate FDA package insert doesn’t have numbers about how common side effects are.

More about fluphenazine decanoate side effects »
How it works
Geodonfluphenazine decanoate
Geodon (Ziprasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar disorder by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.Prolixin Decanoate (fluphenazine decanoate) is a derivative of phenothiazine. It regulates dopamine levels in your brain to control psychotic episodes or schizophrenia.
Type of medication
Geodonfluphenazine decanoate
Prescription onlyPrescription only
Available as
Geodonfluphenazine decanoate
  • Pill
  • Injection
  • Injection
Used for
Geodonfluphenazine decanoate
Risk factors for serious side effects
Geodonfluphenazine decanoate
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • Low potassium
  • Low magnesium
Detailed Geodon (ziprasidone) risks & warnings »
  • People over 65 with dementia and psychosis
  • Taking antipsychotic medications
Detailed Prolixin Decanoate (fluphenazine decanoate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
Geodonfluphenazine decanoate
No alcohol related info.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
Sleep
Geodonfluphenazine decanoate
  • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Weight
Geodonfluphenazine decanoate
  • It causes slightly less weight gain than similar medicines.
No weight related info.
Upsides and benefits
Geodonfluphenazine decanoate
  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
Downsides and risks
Geodonfluphenazine decanoate
  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
Tips from our pharmacists for people taking the medication
Geodonfluphenazine decanoate
  • It usually takes 4 to 6 weeks to see the full effects, so hang in there and wait until it works to figure out the right dose for you.
  • Take Geodon (Ziprasidone) twice a day, preferably with food.
  • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
  • Geodon (Ziprasidone) can cause heart problems, so call your doctor right away if you faint or feel a change in your heartbeat.
  • Let your doctor know if you're taking a diuretic (water pill) or have a condition like chronic diarrhea that'll lower the amount of potassium or magnesium in your blood.
  • Can make you more sensitive to the sun, so wear sunscreen or protective clothing while outside.
  • Can affect how your body regulates your temperature, so drink plenty of liquids especially when you're exercising.
  • Can make it difficult for you to start and stop your movements. Talk to your doctor right away if this happens.
  • Don't combine with alcohol or narcotics since it can stop your breathing.
  • Can make you very sleepy or dizzy. Don't drive or do anything that requires concentration until you know how it affects you.
Learn more
More about GeodonSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Geodon (ziprasidone)?
Worth itNot sureNot worth it
More about fluphenazine decanoateSide effectsAlternativesFDA package insert
Have you used Prolixin Decanoate (fluphenazine decanoate)?
Worth itNot sureNot worth it