Compare Geodon vs. Risperdal

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Geodon (Ziprasidone)

Prescription only

Risperdal (risperidone)

Prescription only
Helps control your thoughts and mood.

Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.

3.4/ 5 average rating with 23 reviewsforGeodon
Helps control your thoughts and mood.

Risperdal (risperidone) is an effective medication in treating schizophrenia, mania, and irritability associated with autism; however, amongst other newer medications in its class, it's more likely to cause side effects, such weight gain and hormone problems.

3.4/ 5 average rating with 45 reviewsforRisperdal
Upsides
  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
  • Risperdal (risperidone) is effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior. It also lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
  • Less likely to cause heart problems compared to other antipsychotics.
  • Compared to other antipsychotics, Risperdal (risperidone) causes less sedation and weight gain.
  • A generic version available for pill, dissolving tablet, and liquid formulations.
Downsides
  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
  • Mild to moderate risk of Extrapyramidal Symptoms (EPS) - movement disorders that cause stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • People taking Risperdal (risperidone) might have weight gain and problems with cholesterol or blood sugar.
  • Compared to other antipsychotics, this medication has a higher risk of hormone problems that can cause nipples to leak and male breasts to grow abnormally large.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • Risperdal (risperidone) takes 4 to 6 weeks for its full effects on thoughts and mood.
Used for
Dosage forms
  • Pill
  • Injection
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
23 reviews so far
43%
saidit'sworth it
43%
saiditworked well
30%
saidit'sa big hassle

Have you used Geodon (Ziprasidone)?

Leave a review
45 reviews so far
42%
saidit'sworth it
47%
saiditworked well
49%
saidit'sa big hassle

Have you used Risperdal (risperidone)?

Leave a review
Side effects
12possible side effects
  • Injection Site Pain
    9%
  • Somnolence
    8%
  • Nausea
    4%
  • Headache
    3%
  • Diarrhea
    3%
  • Dizziness
    3%
  • Insomnia
    3%
  • Asthenia
    2%
  • Hypertension
    2%
  • Anxiety
    2%
  • Agitation
    2%
  • Extrapyramidal Syndrome
    2%
See more detailed side effects
23possible side effects
  • Sedation
    63%
  • Increased appetite
    44%
  • Fatigue
    31%
  • Vomiting
    20%
  • Common cold
    19%
  • Constipation
    17%
  • Cough
    17%
  • Fever
    16%
  • Involuntary urination
    16%
  • Drooling
    12%
  • Headache
    12%
  • Hay fever
    12%
  • Dry mouth
    10%
  • Nasal congestion
    10%
  • Nausea
    8%
  • Upper respiratory tract infection
    8%
  • Weight gain
    8%
  • Tremor
    8%
  • Dizziness
    8%
  • Movement disorder
    8%
  • Rash
    8%
  • Increased saliva
    7%
  • Thirst
    7%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Heart problems
    • History of heart problems
    • Drug interactions
    • Low potassium
    • Low magnesium
  • Neuroleptic malignant syndrome (NMS)
  • Abnormal and involuntary muscle movements
    • Duration of treatment
  • Low blood pressure
  • Risk to fetus
    • Women of childbearing age
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
    • High doses of Risperdal (risperidone)
  • Higher blood sugar and cholesterol and weight gain
    • People with diabetes
    • People with high cholesterol
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings