Compare Geodon vs. Saphris

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Geodon
(Ziprasidone)

Saphris
(Asenapine)

Helps control your thoughts and mood. Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.Coming soon.
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Side effects
GeodonSaphris
  • Drowsiness 19%
  • Extrapyramidal symptoms 19%
  • Dizziness 9%
  • Restlessness 5%
  • Respiratory tract infection 5%
  • Muscle weakness 4%
  • Adverse reaction 3%
  • Vomiting 3%
  • Abnormal vision 3%
  • Accidental injury 2%
More Geodon side effects »

We haven’t found good data for Saphris side effects.

FDA side effect reports for Saphris »
How it works
GeodonSaphris
Geodon (Ziprasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar disorder by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.Coming soon.
Type of medication
GeodonSaphris
Antipsychotic
2nd generation
Prescription only
Coming soon.
Available as
GeodonSaphris
  • Pill
  • Injection
  • Pill
Used for (click to learn more)
GeodonSaphris
  • Bipolar I disorder
Risk factors for serious side effects
GeodonSaphris
  • Elderly patients with dementia
    • History of heart problems
    • Drug interactions
    • Low potassium
    • Low magnesium
      • Duration of treatment
        • Women of childbearing age
        Detailed Geodon (Ziprasidone) risks & warnings »
        Coming soon.
        Pregnancy category
        GeodonSaphris
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        Alcohol
        No specific alcohol-related info.No specific alcohol-related info.
        Food
        • Take Geodon (Ziprasidone) twice a day, preferably with food.
        No specific food-related info.
        Kidneys and liver
        No specific kidneys and liver-related info.No specific kidneys and liver-related info.
        Sex
        No specific sex-related info.No specific sex-related info.
        Sleep
        • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
        No specific sleep-related info.
        Weight
        • It causes slightly less weight gain than similar medicines.
        • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
        No specific weight-related info.
        Upsides and benefits
        GeodonSaphris
        • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
        • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
        • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
        • The Geodon (Ziprasidone) capsule is available as a generic.
        • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
        • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
        Coming soon.
        Downsides and risks
        GeodonSaphris
        • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
        • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
        • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
        • It causes slightly less weight gain than similar medicines.
        • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
        Coming soon.
        Tips from our pharmacists for people taking the medication
        GeodonSaphris
        • It usually takes 4 to 6 weeks to see the full effects, so hang in there and wait until it works to figure out the right dose for you.
        • Take Geodon (Ziprasidone) twice a day, preferably with food.
        • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
        • Geodon (Ziprasidone) can cause heart problems, so call your doctor right away if you faint or feel a change in your heartbeat.
        • Let your doctor know if you're taking a diuretic (water pill) or have a condition like chronic diarrhea that'll lower the amount of potassium or magnesium in your blood.
        Coming soon.
        Learn more
        More about GeodonSide effectsReviews & ratingsAlternativesFDA package insert
        More about SaphrisSide effectsReviews & ratingsFDA package insert