Compare Gilenya vs. Aubagio

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Gilenya (Fingolimod)

Prescription only

Aubagio (Teriflunomide)

Prescription only
Treats relapsing forms of multiple sclerosis.

Gilenya (Fingolimod) is an oral medication that has a lot of side effects, but it reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS.

4.0/ 7 average rating with 57 reviewsforGilenya
Treats relapsing forms of MS.

Aubagio (Teriflunomide) is an oral medicine that effectively reduces the number of flare-ups, slows physical changes, and decreases the number of new brain lesions in relapsing MS. Because it stays in the body for so long, if you have a serious reaction or possible pregnancy you'll need to have it quickly removed with another medicine.

3.3/ 7 average rating with 23 reviewsforAubagio
Upsides
  • Gilenya (Fingolimod) is the first once-daily pill you can take for relapsing forms of multiple sclerosis (MS).
  • Studies show it lowers relapse rates better than placebo and Avonex, and it delays the progression of physical disabilites better than placebo.
  • Gilenya also reduced the number of new MS lesions better than Avonex.
  • You can take it by mouth.
  • It comes a 7 mg and 14mg dose and only needs to be taken once a day, with or without food.
  • In clinical studies, Aubagio reduced relapses, slowed disability, and decreased the number of new brain lesions compared to sugar pill (placebo).
  • Although it may not work for everyone, most people felt it wasn't much of a hassle.
Downsides
  • Taking more than the 0.5 mg dose won't give more benefits, but will only cause more side effects.
  • Gilenya can remain in your blood for up to 2 months after you stop taking it. Your immune response won't work as well during this time.
  • Not the best choice if you've had a heart attack, stroke, or have been in the hospital for heart failure in the past 6 months. The risk of serious heart rate effects is higher when taken with certain drugs (methadone, erythromycin, citalopram, ketoconazole) or if you have low potassium or magnesium.
  • If you have to re-start Gilenya after stopping it for 2 weeks or more, you'll have to take your first dose at your doctor's office again.
  • If you didn't get chicken pox and never had a vaccination, you'll need to be vaccinated and wait one month before starting Gilenya.
  • Some people have nausea and diarrhea when they start treatment. In most cases, these effects are mild and get better over time.
  • Aubagio can cause your hair to thin. This is temporary, and your hair will go back to normal after a few months.
  • You should have certain lab tests to make sure you don't have any problems from taking Aubagio. These include: complete blood count and liver enzyme testing within 6 months before you start treatment, tuberculosis (TB) screening, and blood pressure.
  • Numbness or tingling in your hands and feet (peripheral neuropathy), different from MS was reported more often than with sugar pill (placebo)
  • Aubagio may stay in your blood up to 2 years after you stop taking it. You can quickly remove Aubagio the accelerated elimination procedure, but symptoms of your disease may return.
  • You can't take it if you're pregnant.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$5558.31
Find instant savings
Lowest price near you
$17675.5
Find instant savings
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
57 
42%
think this treatment is worth it
30%
think this treatment works well
30%
think this treatment is a hassle

Have you used Gilenya (Fingolimod)?

Leave a review
23 
43%
think this treatment is worth it
26%
think this treatment works well
30%
think this treatment is a hassle

Have you used Aubagio (Teriflunomide)?

Leave a review
Side effects
10possible side effects
  • Headache
    25%
  • ALT/AST increased
    14%
  • Influenza viral infections
    13%
  • Diarrhea
    12%
  • Back pain
    12%
  • Cough
    10%
  • Herpes viral infections
    9%
  • Bronchitis
    8%
  • Dyspnea
    8%
  • Depression
    8%
See more detailed side effects
1possible side effects
  • Moderate hypophospatemia
    5%
See more detailed side effects
Risks and warnings
  • Heart problems

    Taking with drugs that slow heart rate

    ...and 1 more risk factors

  • Serious infections

    Taking other immunosuppressant drugs

    ...and 2 more risk factors

  • Eye problems

    Diabetes

    ...and 1 more risk factors

  • Risk to fetus

    Women of childbearing age

  • Respiratory problems

    History of respiratory problems

  • Liver problems

    History of liver problems

See more detailed risks and warnings
  • Liver problems

    Taking medicines that affect your liver or cause liver injury

  • Serious skin reactions

    Reaction to leflunomide

  • Numbness in extremities (hands and feet)

    Age 60 or older

    ...and 2 more risk factors

  • Serious Infections

    Taking other immunosuppressant drugs

    ...and 2 more risk factors

  • Kidney problems

    High uric acid levels

  • High potassium

    Acute kidney failure

  • Respiratory problems

    History of lung disease

  • High blood pressure

    History of high blood pressure

See more detailed risks and warnings