Compare Glucotrol vs. Metaglip

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Glucotrol
(glipizide)

Metaglip
(metformin / glipizide)

Lowers blood sugar. Glucotrol (Glipizide) is a very effective oral blood sugar-lowering medicine. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.Coming soon.
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Coupons for Glucotrol
Best available price for 60 (5mg) tablets of glipizide
Coupons for Metaglip
Best available price for 60 (5mg/500mg) tablets of metaglip
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.29Glucotrol
Reviews for Glucotrol
50%
of people (All ages) say Glucotrol is worth it
32%
say it works well
19%
say it's a big hassle
332 reviews
Have you used Glucotrol (glipizide)?
Worth itNot sureNot worth it

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Have you used Metaglip (metformin / glipizide)?
Worth itNot sureNot worth it
Side effects
GlucotrolMetaglip
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Drowsiness 2%
More Glucotrol side effects »

We haven’t found good data for Metaglip side effects.

FDA side effect reports for Metaglip »
How it works
GlucotrolMetaglip
Glucotrol (Glipizide) is an anti-diabetic drug. It stimulates your body to make more insulin to lower blood sugar.Coming soon.
Type of medication
GlucotrolMetaglip
Prescription only
Available as
GlucotrolMetaglip
  • Pill
  • Extended release
  • Pill
Used for
GlucotrolMetaglip
  • Diabetes Mellitus Type 2
Risk factors for serious side effects
GlucotrolMetaglip
  • Use of other blood sugar lowering medicines
  • Alcohol
  • Intense physical activity
  • History of sulfa allergies
Detailed Glucotrol (glipizide) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    GlucotrolMetaglip
    • Avoid drinking alcohol.
    No alcohol related info.
    Food
    GlucotrolMetaglip
    • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
    • Eat regular, balanced meals to avoid low blood sugar.
    No food related info.
    Kidneys and liver
    GlucotrolMetaglip
    • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
    No kidneys and liver related info.
    Weight
    GlucotrolMetaglip
    • Can cause mild weight gain (2 to 3 pounds).
    • Can cause weight gain, dizziness, or stomach upset.
    No weight related info.
    Upsides and benefits
    GlucotrolMetaglip
    • Oral blood sugar-lowering medicine.
    • Lowers A1c levels by 1-2%. (Hemoglobin A1c measures your average blood sugar over time.)
    • Prevents the harmful effects of high sugar levels on your organs and blood vessels.
    • Might be a better choice for people with kidney problems compared to similar drugs because Glipizide isn't processed by the kidneys.
    • One of the least expensive diabetes medicines.
    Coming soon
    Downsides and risks
    GlucotrolMetaglip
    • Higher risk of low blood sugar episodes than other kinds of oral diabetes medicines.
    • You have to check your blood sugar 2 to 5 times a week (less often once you are on a stable dose).
    • Can cause mild weight gain (2 to 3 pounds).
    • Loses effectiveness over time or as your body stops making insulin.
    • Food can cause unpredictable effects of the immediate-release version of Glipizide, so you have to take it at least 30 minutes before a meal.
    Coming soon
    Tips from our pharmacists for people taking the medication
    GlucotrolMetaglip
    • Works best if you take it 30 minutes before a meal, usually your first big meal of the day.
    • Can cause weight gain, dizziness, or stomach upset.
    • Avoid drinking alcohol.
    • Eat regular, balanced meals to avoid low blood sugar.
    • Check your blood sugar regularly.
    Coming soon
    Learn more
    More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Glucotrol (glipizide)?
    Worth itNot sureNot worth it
    More about MetaglipSide effectsFDA package insert
    Have you used Metaglip (metformin / glipizide)?
    Worth itNot sureNot worth it