Compare glyburide vs. Human Insulin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
This form of insulin is one of the few medications in its class that you can get without a prescription, but it's expensive.
- Available as an oral tablet.
- Lowers your A1c (average blood sugar over time) up to 2%.
- Available in generic version.
- Available in single pill combination with other anti-diabetic medicines.
- Some types of this medication are available without a prescription.
- Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose.
- Available in different combinations so that you can do one shot or multiple shots a day.
- More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
- You will have to check your blood sugar often when you first start taking it.
- Can cause weight gain (about 2 to 3 pounds).
- Not ideal for elderly or those with poor kidney function.
- May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
- Has to be taken exactly as directed or it can cause high or low blood sugar.
- As with all insulins, you have to work with your doctor closely to make sure you're giving yourself the correct dose, or you can have low or high blood sugar.
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- Low blood sugar
Over age 65
...and 4 more risk factors
- Severe allergic reactions
History of sulfa allergies