Compare triazolam vs. chlordiazepoxide / amitriptyline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

triazolam

chlordiazepoxide / amitriptyline

Helps you stay asleep. Halcion (triazolam) can be used to help you fall asleep, but your body can become used to it very quickly.Treats anxiety and depression. While Limbitrol (chlordiazepoxide / amitriptyline) as a combination can be used to treat both anxiety and depression, other medicines are considered first choice because chlordiazepoxide can be potentially addicting.
Reviews & ratings
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Have you used Halcion (triazolam)?
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Have you used Limbitrol (chlordiazepoxide / amitriptyline)?
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Side effects
triazolamchlordiazepoxide / amitriptyline
  • Nausea and vomiting 1%
  • Difficulty controlling movements 4%
  • Lightheadedness 4%
  • Dizziness 5%
  • Headache 2%
  • Drowsiness 8%
More triazolam side effects »

The chlordiazepoxide / amitriptyline FDA package insert doesn’t have numbers about how common side effects are.

More about chlordiazepoxide / amitriptyline side effects »
How it works
triazolamchlordiazepoxide / amitriptyline
Halcion (triazolam) is a benzodiazepine. It helps you stay asleep by extending how long you stay asleep, and improving the quality of your sleep so you don't wake up as much at night.Limbitrol (chlordiazepoxide / amitriptyline) is a combination of 2 medicines. Chlordiazepoxide is a benzodiazepine, and it calms activity in a part of the brain responsible for emotional responses. Amitriptyline is a tricyclic antidepressant, and it raises the amount of norepinephrine and serotonin in the brain, which can improve mood.
Type of medication
triazolamchlordiazepoxide / amitriptyline
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
triazolamchlordiazepoxide / amitriptyline
  • Pill
  • Pill
Used for
triazolamchlordiazepoxide / amitriptyline
  • Anxiety And Depression
Risk factors for serious side effects
triazolamchlordiazepoxide / amitriptyline
  • Using Halcion (triazolam) for more than 10 days
  • People age 65 or older
  • Drinking alcohol
  • Not allowing enough time for sleep
Detailed Halcion (triazolam) risks & warnings »
  • People under age 24
  • Glaucoma
  • Heart disease
  • Alcohol
  • Taking narcotics, tranquilizers, or antihistamines
Detailed Limbitrol (chlordiazepoxide / amitriptyline) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
triazolamchlordiazepoxide / amitriptyline
  • Don't drink alcohol while taking Halcion (triazolam) since it can slow your breathing.
  • Don't drink alcohol or take narcotics, tranquilizers, or antihistamines if you're taking Limbitrol (chlordiazepoxide / amitriptyline). This can slow down your breathing. Talk to your doctor if this is a problem.
  • Don't drink alcohol or take any narcotics while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can slow your breathing.
Sleep
triazolamchlordiazepoxide / amitriptyline
  • People taking Halcion (triazolam) for sleep while fighting jet lag have reported not being able to remember what happened a few hours after taking the medicine. This is more likely to happen if you drink alcohol, or if you don't have enough time to sleep. Give yourself at least 7 to 8 hours to sleep to stop this from happening.
  • Limbitrol (chlordiazepoxide / amitriptyline) can make you sleepy and unable to focus, so don't drive or do anything requiring concentration for a few hours after taking it until you know how it affects you. This can be worse if you drink alcohol or take narcotics.
Upsides and benefits
triazolamchlordiazepoxide / amitriptyline
  • Halcion (triazolam) is available as a generic.
  • Compared to other similar medicines, you're less likely to have a hangover effect from Halcion (triazolam) the next day.
  • Limbitrol (chlordiazepoxide / amitriptyline) is available as a generic.
  • Limbitrol (chlordiazepoxide / amitriptyline) works faster than amitriptyline alone.
Downsides and risks
triazolamchlordiazepoxide / amitriptyline
  • Your body can get used to Halcion (triazolam) after 2 weeks.
  • Stopping Halcion (triazolam) suddenly can make your insomnia worse. Talk to your doctor if you want to stop taking it.
  • People who take Halcion (triazolam) can have more anxiety during the day.
  • Limbitrol (chlordiazepoxide / amitriptyline) is only available in certain strengths, so it can be difficult to customize a dose that treats both anxiety and depression.
  • Limbitrol (chlordiazepoxide / amitriptyline) contains chlordiazepoxide, which can be potentially addicting.
  • You might not notice any changes in your mood until you've been taking Limbitrol (chlordiazepoxide / amitriptyline) for several weeks.
  • Amitriptyline alone is considered a better treatment for anxiety and depression than Limbitrol (chlordiazepoxide / amitriptyline).
  • Other medicines are considered first choice for treating anxiety and depression over Limbitrol (chlordiazepoxide / amitriptyline).
Tips from our pharmacists for people taking the medication
triazolamchlordiazepoxide / amitriptyline
  • Take Halcion (triazolam) on an empty stomach; otherwise, it won't work as well.
  • Don't drink alcohol while taking Halcion (triazolam) since it can slow your breathing.
  • You should only use Halcion (triazolam) for 7 to10 days. If it doesn't help you sleep, talk to your doctor.
  • You might have a hangover-like feeling the next day after taking Halcion (triazolam). Be careful driving or doing anything requiring concentration until you know how your body reacts to it.
  • Only take Halcion (triazolam) if you know you're going to bed right away.
  • Don't drink alcohol or take any narcotics while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can slow your breathing.
  • If you've taken Limbitrol (chlordiazepoxide / amitriptyline) for an extended amount of time, don't stop taking it suddenly without talking to your doctor first. It can be very dangerous.
  • Don't drive or do anything requiring concentration while taking Limbitrol (chlordiazepoxide / amitriptyline) since it can make you sleepy. This can be worse if you drink alcohol or take narcotics.
  • You might not notice changes in your mood until you've taken Limbitrol (chlordiazepoxide / amitriptyline) for at least a few weeks.
  • If you're being switched to Limbitrol (chlordiazepoxide / amitriptyline) from a group of medicines called monoamine oxidase inhibitors (MAOI), you should wait at least 14 days before you start.
Learn more
More about triazolamSide effectsAlternativesFDA package insert
Have you used Halcion (triazolam)?
Worth itNot sureNot worth it
More about chlordiazepoxide / amitriptylineSide effectsAlternativesFDA package insert
Have you used Limbitrol (chlordiazepoxide / amitriptyline)?
Worth itNot sureNot worth it