Compare triazolam vs. desipramine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Halcion
(triazolam)

Norpramin
(desipramine)

Helps you stay asleep. Halcion (triazolam) can be used to help you fall asleep, but your body can become used to it very quickly.Stabilizes your mood. Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven't worked.
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Coupons for triazolam
Best available price for 30 (0.25mg) tablets of triazolam
Coupons for desipramine
Best available price for 30 (25mg) tablets of desipramine
Reviews & ratings
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Have you used Halcion (triazolam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Norpramin (desipramine)?
Worth itNot sureNot worth it
Side effects
triazolamdesipramine
  • Drowsiness 8%
  • Headache 2%
  • Dizziness 5%
  • Nausea and vomiting 1%
  • Difficulty controlling movements 4%
  • Lightheadedness 4%
More triazolam side effects »

The desipramine FDA package insert doesn’t have numbers about how common side effects are.

More about desipramine side effects »
How it works
triazolamdesipramine
Halcion (triazolam) is a benzodiazepine. It helps you stay asleep by extending how long you stay asleep, and improving the quality of your sleep so you don't wake up as much at night.Norpramin (desipramine) is a tricyclic antidepressant. It increases the amount of norepinephrine and serotonin in the brain, two chemicals that regulate mood.
Type of medication
triazolamdesipramine
Prescription onlyPrescription only
Available as
triazolamdesipramine
  • Pill
  • Pill
Used for
triazolamdesipramine
Risk factors for serious side effects
triazolamdesipramine
  • Using Halcion (triazolam) for more than 10 days
  • People age 65 or older
  • Drinking alcohol
  • Not allowing enough time for sleep
Detailed Halcion (triazolam) risks & warnings »
  • People under age 24
  • Tricyclic antidepressants
  • Fentanyl
  • Tramadol
  • Buspirone
Detailed Norpramin (desipramine) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
triazolamdesipramine
  • Don't drink alcohol while taking Halcion (triazolam) since it can slow your breathing.
No alcohol related info.
Sleep
triazolamdesipramine
  • People taking Halcion (triazolam) for sleep while fighting jet lag have reported not being able to remember what happened a few hours after taking the medicine. This is more likely to happen if you drink alcohol, or if you don't have enough time to sleep. Give yourself at least 7 to 8 hours to sleep to stop this from happening.
No sleep related info.
Upsides and benefits
triazolamdesipramine
  • Halcion (triazolam) is available as a generic.
  • Compared to other similar medicines, you're less likely to have a hangover effect from Halcion (triazolam) the next day.
  • Norpramin (desipramine) is available in generic and in many different strengths, so the dose can be more customized.
  • Norpramin (desipramine) has fewer side effects than similar tricyclic antidepressants.
Downsides and risks
triazolamdesipramine
  • Your body can get used to Halcion (triazolam) after 2 weeks.
  • Stopping Halcion (triazolam) suddenly can make your insomnia worse. Talk to your doctor if you want to stop taking it.
  • People who take Halcion (triazolam) can have more anxiety during the day.
  • Norpramin (desipramine) isn't recommended if you or your family has heart disease, seizures, or glaucoma.
  • Norpramin (desipramine) isn't a first choice for depression because it has more side effects than other antidepressants.
  • In some people, Norpramin (desipramine) can make you sleepy. In other people, Norpramin (desipramine) can keep you awake.
  • If you have diabetes, Norpramin (desipramine) can make your blood sugar go up.
  • Not recommended in children under 12 years of age.
Tips from our pharmacists for people taking the medication
triazolamdesipramine
  • Take Halcion (triazolam) on an empty stomach; otherwise, it won't work as well.
  • Don't drink alcohol while taking Halcion (triazolam) since it can slow your breathing.
  • You should only use Halcion (triazolam) for 7 to10 days. If it doesn't help you sleep, talk to your doctor.
  • You might have a hangover-like feeling the next day after taking Halcion (triazolam). Be careful driving or doing anything requiring concentration until you know how your body reacts to it.
  • Only take Halcion (triazolam) if you know you're going to bed right away.
  • Don't drive or do anything requiring concentration until you know how Norpramin (desipramine) affects you since it can make you feel sleepy.
  • Talk to your doctor right away if your mood suddenly darkens and you want to hurt yourself while taking Norpramin (desipramine).
  • If you're being switched to Norpramin (desipramine) from monoamine oxidase inhibitors, you'll need to wait 2 weeks before you can start it.
  • Don't stop taking Norpramin (desipramine) suddenly without talking to your doctor first.
Learn more
More about triazolamSide effectsAlternativesFDA package insert
Have you used Halcion (triazolam)?
Worth itNot sureNot worth it
More about desipramineSide effectsAlternativesFDA package insert
Have you used Norpramin (desipramine)?
Worth itNot sureNot worth it