Compare Haldol vs. fluphenazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Haldol (haloperidol)

Prescription only

Prolixin (fluphenazine)

Prescription only
Helps control your thoughts, calm agitation, and stabilize your mood.

Haldol (haloperidol) is less likely to cause weight gain and sedation, but more likely to cause movement disorders compared to other antipsychotics.

3.1/ 5 average rating with 50 reviewsforHaldol
Treats schizophrenia and psychosis.

Prolixin (fluphenazine) can stabilize your mood. It is used to find the right dose for you before moving to a long-acting injection.

Upsides
  • Haldol (haloperidol) is available in a cheap, generic version.
  • A monthly extended-release injection allows for more convenient dosing than a daily pill.
  • Good at stabilizing your mood.
  • Available in several oral and injectable forms, including a long-acting injection that is taken less frequently.
Downsides
  • Haldol (haloperidol) is an older medicine and has a lot more problematic side effects compared to newer antipsychotics.
  • You might need routine blood tests and regular check-ups to make sure the medicine is working for you.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can make it difficult for you to control your movements if you've been on Prolixin (fluphenazine) for a while.
Used for
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Pill
  • Liquid
  • Injection
Price
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Reviews
50 reviews so far
38%
saidit'sworth it
42%
saiditworked well
34%
saidit'sa big hassle

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Side effects
The Haldol (haloperidol) FDA package insert doesn’t have numbers about how common side effects are.
The Prolixin (fluphenazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Increased risk of death
    • People over 65 with dementia and psychosis
  • Difficulty controlling movements
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Low white blood cell count
See more detailed risks and warnings