Compare Haldol vs. Geodon

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Haldol
(Haloperidol)

Geodon
(Ziprasidone)

Helps control your thoughts and calms agitation. Haldol (Haloperidol) is okay for treating psychosis and agitation. It's less likely to cause weight gain than other antipsychotics, but it's more likely to cause other bad side effects.Helps control your thoughts and mood. Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.
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Reviews & ratings
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4.081632653061225Haldol
Reviews for Haldol (Haloperidol)
37%
of people say Haldol (Haloperidol) is worth it
41%
say it works well
35%
say it's a big hassle

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Side effects
HaldolGeodon

The Haldol FDA package insert doesn’t have numbers about how common side effects are.

More about Haldol side effects »
  • Drowsiness 19%
  • Extrapyramidal symptoms 19%
  • Dizziness 9%
  • Restlessness 5%
  • Respiratory tract infection 5%
  • Muscle weakness 4%
  • Adverse reaction 3%
  • Vomiting 3%
  • Abnormal vision 3%
  • Accidental injury 2%
More Geodon side effects »
How it works
HaldolGeodon
Haldol (Haloperidol) is a traditional antipsychotic. Researchers don't know exactly how it works, but it seems to change dopamine activity in your brain, which affects thoughts and mood.Geodon (Ziprasidone) is a second generation antipsychotic. It treats schizophrenia and bipolar disorder by adjusting the levels of dopamine and serotonin in your brain, which affects thoughts and mood.
Type of medication
HaldolGeodon
Antipsychotic
Typical
Prescription only
Antipsychotic
2nd generation
Prescription only
Available as
HaldolGeodon
  • Pill
  • Liquid
  • Injection
  • Pill
  • Injection
Used for (click to learn more)
HaldolGeodon
Risk factors for serious side effects
HaldolGeodon
  • Elderly patients with dementia
      • History of heart problems
      • Drug interactions
        • People with diabetes
        • People with high cholesterol
        • People with diabetes
        • Alcohol
        • Taking other medicines that make you less alert
          Detailed Haldol (Haloperidol) risks & warnings »
          • Elderly patients with dementia
            • History of heart problems
            • Drug interactions
            • Low potassium
            • Low magnesium
              • Duration of treatment
                • Women of childbearing age
                Detailed Geodon (Ziprasidone) risks & warnings »
                Pregnancy category
                HaldolGeodon
                CFDA pregnancy category (Weigh risks vs. benefits)

                Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                See the FDA package insert
                CFDA pregnancy category (Weigh risks vs. benefits)

                Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

                See the FDA package insert
                Alcohol
                No specific alcohol-related info.No specific alcohol-related info.
                Food
                • Haldol (Haloperidol) can increase your blood sugar and cholesterol. However, Haldol (Haloperidol) is less likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
                • Haldol (Haloperidol) can cause you to gain weight. However, Haldol (Haloperidol) is less likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
                • Take Geodon (Ziprasidone) twice a day, preferably with food.
                Kidneys and liver
                No specific kidneys and liver-related info.No specific kidneys and liver-related info.
                Sex
                No specific sex-related info.No specific sex-related info.
                Sleep
                • It can cause dizziness, drowsiness, and can lower your blood pressure.
                • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
                Weight
                • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
                • Haldol (Haloperidol) can cause you to gain weight. However, Haldol (Haloperidol) is less likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
                • It causes slightly less weight gain than similar medicines.
                • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
                Upsides and benefits
                HaldolGeodon
                • Effective at relieving psychotic symptoms and agitation.
                • Works just as well as other antipsychotic medicines.
                • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
                • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
                • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
                • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
                • The Geodon (Ziprasidone) capsule is available as a generic.
                • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
                • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
                Downsides and risks
                HaldolGeodon
                • It's an older medicine and has a lot more side effects than newer antipsychotics.
                • Compared to other antipsychotics, it causes more hormone problems that can cause nipples to leak fluid, and sudden, dangerous abnormal heart rhythms.
                • Has a higher risk of extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements. One of these symptoms (called tardive dyskinesia) is permanent and more likely if you take this medicine for many years.
                • You might need routine blood tests to check how the medicine is affecting your body.
                • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
                • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
                • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
                • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
                • It causes slightly less weight gain than similar medicines.
                • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
                Tips from our pharmacists for people taking the medication
                HaldolGeodon
                • It'll take 4 to 6 weeks to see the medication's full effects on your thoughts.
                • It can cause dizziness, drowsiness, and can lower your blood pressure.
                • For the first week, avoid activities like driving that require you to be alert.
                • Immediately tell your doctor if you can't control your muscle movements or if you have a fever or excess sweating.
                • Don't use in elderly people who have dementia.
                • The oral liquid concentrate can be mixed with water or juice before taking it.
                • It usually takes 4 to 6 weeks to see the full effects, so hang in there and wait until it works to figure out the right dose for you.
                • Take Geodon (Ziprasidone) twice a day, preferably with food.
                • Can cause drowsiness when you first start taking it, so avoid activities that require you to be alert until you know how it affects you.
                • Geodon (Ziprasidone) can cause heart problems, so call your doctor right away if you faint or feel a change in your heartbeat.
                • Let your doctor know if you're taking a diuretic (water pill) or have a condition like chronic diarrhea that'll lower the amount of potassium or magnesium in your blood.
                Learn more
                More about HaldolSide effectsReviews & ratingsAlternativesFDA package insert
                More about GeodonSide effectsReviews & ratingsAlternativesFDA package insert