Compare Haldol vs. loxapine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Haldol
(haloperidol)

Loxitane
(loxapine)

Helps control your thoughts and calms agitation. Haldol (Haloperidol) is okay for treating psychosis and agitation. It's less likely to cause weight gain than other antipsychotics, but it's more likely to cause other bad side effects.Treats schizophrenia. Loxitane (loxapine) is not recommended as a first choice medicine for treatment of schizophrenia, but it can be good if other medicines haven't worked because of bad side effects.
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Coupons for Haldol
Best available price for 30 (5mg) tablets of haloperidol
Coupons for loxapine
Best available price for 60 (10mg) capsules of loxapine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.12Haldol
Reviews for Haldol
38%
of people (All ages) say Haldol is worth it
42%
say it works well
34%
say it's a big hassle
Have you used Haldol (haloperidol)?
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Have you used Loxitane (loxapine)?
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Side effects
Haldolloxapine

The Haldol FDA package insert doesn’t have numbers about how common side effects are.

More about Haldol side effects »

The loxapine FDA package insert doesn’t have numbers about how common side effects are.

More about loxapine side effects »
How it works
Haldolloxapine
Haldol (Haloperidol) is a traditional antipsychotic. Researchers don't know exactly how it works, but it seems to change dopamine activity in your brain, which affects thoughts and mood.Loxitane (loxapine) is a typical antipsychotic. It works in the brain to calm down parts of the brain that might be responsible for aggressive behavior.
Type of medication
Haldolloxapine
Prescription onlyPrescription only
Available as
Haldolloxapine
  • Pill
  • Liquid
  • Injection
  • Pill
Used for
Haldolloxapine
Risk factors for serious side effects
Haldolloxapine
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Haldol (haloperidol) risks & warnings »
  • People age 65 and older with dementia and psychosis
  • Taking antipsychotic medications
  • History of seizures
Detailed Loxitane (loxapine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
Haldolloxapine
No alcohol related info.
  • Don't drink alcohol or take narcotics while taking Loxitane (loxapine) since you can have problems breathing.
Food
Haldolloxapine
  • Haldol (Haloperidol) can increase your blood sugar and cholesterol. However, Haldol (Haloperidol) is less likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Take Loxitane (loxapine) with food to avoid stomach upset.
Sleep
Haldolloxapine
  • It can cause dizziness, drowsiness, and can lower your blood pressure.
No sleep related info.
Weight
Haldolloxapine
  • Haldol (Haloperidol) can cause you to gain weight. However, Haldol (Haloperidol) is less likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
No weight related info.
Upsides and benefits
Haldolloxapine
  • Effective at relieving psychotic symptoms and agitation.
  • Works just as well as other antipsychotic medicines.
  • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
  • Loxitane (loxapine) can be used to control schizophrenia if other medicines haven't worked because you don't like their side effects.
  • Loxitane (loxapine) is available as a generic.
Downsides and risks
Haldolloxapine
  • It's an older medicine and has a lot more side effects than newer antipsychotics.
  • Compared to other antipsychotics, it causes more hormone problems that can cause nipples to leak fluid, and sudden, dangerous abnormal heart rhythms.
  • Has a higher risk of extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements. One of these symptoms (called tardive dyskinesia) is permanent and more likely if you take this medicine for many years.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
  • Loxitane (loxapine) is not recommended as a first choice for treating schizophrenia because it's more likely to cause trouble with controlling movements.
  • Loxitane (loxapine) can stop vomiting, so it can be difficult to tell if someone's overdosed on drugs.
  • Loxitane (loxapine) can raise heart rate and lower blood pressure.
Tips from our pharmacists for people taking the medication
Haldolloxapine
  • It'll take 4 to 6 weeks to see the medication's full effects on your thoughts.
  • It can cause dizziness, drowsiness, and can lower your blood pressure.
  • For the first week, avoid activities like driving that require you to be alert.
  • Immediately tell your doctor if you can't control your muscle movements or if you have a fever or excess sweating.
  • Don't use in elderly people who have dementia.
  • The oral liquid concentrate can be mixed with water or juice before taking it.
  • Take Loxitane (loxapine) with food to avoid stomach upset.
  • Don't drive or do anything requiring concentration until you know how Loxitane (loxapine) affects you since it can make you sleepy.
  • Don't drink alcohol or take narcotics while taking Loxitane (loxapine) since you can have problems breathing.
  • Be very careful getting up if you've been sitting or lying down for a while as Loxitane (loxapine) can cause changes in your blood pressure, which might make you more likely to faint or fall.
Learn more
More about HaldolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Haldol (haloperidol)?
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More about loxapineSide effectsAlternativesFDA package insert
Have you used Loxitane (loxapine)?
Worth itNot sureNot worth it