Compare Haldol vs. thiothixene

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Haldol
(haloperidol)

Navane
(thiothixene)

Helps control your thoughts and calms agitation. Haldol (Haloperidol) is okay for treating psychosis and agitation. It's less likely to cause weight gain than other antipsychotics, but it's more likely to cause other bad side effects.Treats schizophrenia. Navane (thiothixene) isn't a first choice for treating schizophrenia because of the side effects, but it is cheaper than other medicines.
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Coupons for Haldol
Best available price for 30 (5mg) tablets of haloperidol
Coupons for thiothixene
Best available price for 30 (5mg) capsules of thiothixene
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.12Haldol
Reviews for Haldol
38%
of people (All ages) say Haldol is worth it
42%
say it works well
34%
say it's a big hassle
Have you used Haldol (haloperidol)?
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Have you used Navane (thiothixene)?
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Side effects
Haldolthiothixene

The Haldol FDA package insert doesn’t have numbers about how common side effects are.

More about Haldol side effects »

The thiothixene FDA package insert doesn’t have numbers about how common side effects are.

More about thiothixene side effects »
How it works
Haldolthiothixene
Haldol (Haloperidol) is a traditional antipsychotic. Researchers don't know exactly how it works, but it seems to change dopamine activity in your brain, which affects thoughts and mood.Navane (thiothixene) is a typical antipsychotic. It works by lowering levels of dopamine in the brain. It's believed that schizophrenia might be caused by the brain being too sensitive to changes in dopamine.
Type of medication
Haldolthiothixene
Prescription onlyPrescription only
Available as
Haldolthiothixene
  • Pill
  • Liquid
  • Injection
  • Pill
Used for
Haldolthiothixene
Risk factors for serious side effects
Haldolthiothixene
  • Elderly patients with dementia
  • History of heart problems
  • Drug interactions
  • People with diabetes
  • People with high cholesterol
Detailed Haldol (haloperidol) risks & warnings »
  • People age 65 or older with dementia and psychosis
  • Drinking alcohol, or taking opioids, benzodiazepines, or sleeping medicines
Detailed Navane (thiothixene) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
Haldolthiothixene
No alcohol related info.
  • Don't drink alcohol while taking Navane (thiothixene).
Food
Haldolthiothixene
  • Haldol (Haloperidol) can increase your blood sugar and cholesterol. However, Haldol (Haloperidol) is less likely to raise your blood sugar and cholesterol compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Take Navane (thiothixene) with food so you don't get an upset stomach.
Sleep
Haldolthiothixene
  • It can cause dizziness, drowsiness, and can lower your blood pressure.
  • Navane (thiothixene) can make you sleepy and unable to focus, so don't drive or do anything requiring concentration for a few hours after taking it until you know how Navane (thiothixene) affects your concentration. This can be worse if you drink alcohol or take medicines that can make you sleepy, such as opioids for pain, benzodiazepines for anxiety, or medicines to help you sleep.
Weight
Haldolthiothixene
  • Haldol (Haloperidol) can cause you to gain weight. However, Haldol (Haloperidol) is less likely to cause weight gain compared to other antipsychotic medications. Exercise and eat healthy food to lower your risk.
  • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
  • Side effects include weight gain and high blood sugar.
Upsides and benefits
Haldolthiothixene
  • Effective at relieving psychotic symptoms and agitation.
  • Works just as well as other antipsychotic medicines.
  • Less likely to cause weight gain and problems with cholesterol and blood sugar than most other antipsychotics.
  • Navane (thiothixene) is available in generic.
  • Navane (thiothixene) is less likely to make you sleepy.
Downsides and risks
Haldolthiothixene
  • It's an older medicine and has a lot more side effects than newer antipsychotics.
  • Compared to other antipsychotics, it causes more hormone problems that can cause nipples to leak fluid, and sudden, dangerous abnormal heart rhythms.
  • Has a higher risk of extrapyramidal symptoms (EPS): movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements. One of these symptoms (called tardive dyskinesia) is permanent and more likely if you take this medicine for many years.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics have side effects that make them difficult to take. You might need to try a few different medicines until you find one that works best for you.
  • Side effects include weight gain and high blood sugar.
  • Navane (thiothixene) can cause low blood pressure, which can cause fainting or falls if you’re not careful.
  • Smoking tobacco can make Navane (thiothixene) work poorly.
Tips from our pharmacists for people taking the medication
Haldolthiothixene
  • It'll take 4 to 6 weeks to see the medication's full effects on your thoughts.
  • It can cause dizziness, drowsiness, and can lower your blood pressure.
  • For the first week, avoid activities like driving that require you to be alert.
  • Immediately tell your doctor if you can't control your muscle movements or if you have a fever or excess sweating.
  • Don't use in elderly people who have dementia.
  • The oral liquid concentrate can be mixed with water or juice before taking it.
  • Don't drive or do anything requiring concentration until you know how Navane (thiothixene) affects you.
  • You might not notice any changes in your behavior until you've taken Navane (thiothixene) for at least 4 weeks.
  • Navane (thiothixene) can cause low blood pressure. Be very careful getting up if you've been sitting or lying down for a while since you can feel faint.
  • Navane (thiothixene) can make it hard to control your body temperature. Be careful exercising, especially in the heat, and dress warmly if it's cold.
  • Take Navane (thiothixene) with food so you don't get an upset stomach.
  • Don't drink alcohol while taking Navane (thiothixene).
Learn more
More about HaldolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Haldol (haloperidol)?
Worth itNot sureNot worth it
More about thiothixeneSide effectsAlternativesFDA package insert
Have you used Navane (thiothixene)?
Worth itNot sureNot worth it