Compare Human Insulin vs. Apidra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Humulin (Human Insulin)

Prescription only
Lowers blood sugar.

This form of insulin is one of the few medications in its class that you can get without a prescription, but it's expensive.

3.6/ 5 average rating with 57 reviewsforHuman Insulin
Controls blood sugar.

Apidra (insulin glulisine) is an insulin that controls blood sugar during your meals, but you'll still have to follow your doctor's diet and exercise plan.

Upsides
  • Some types of this medication are available without a prescription.
  • Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose.
  • Available in different combinations so that you can do one shot or multiple shots a day.
  • Apidra (insulin glulisine) starts working in as soon as 15 minutes.
  • Programs are available to lower your copay. Talk to your doctor or pharmacist.
  • Can be used in people over 65 and children 4 years of age and older.
Downsides
  • Has to be taken exactly as directed or it can cause high or low blood sugar.
  • As with all insulins, you have to work with your doctor closely to make sure you're giving yourself the correct dose, or you can have low or high blood sugar.
  • Your doctor might have to check your kidneys and liver regularly if you've had kidney or liver problems in the past.
  • Since Apidra (insulin glulisine) is an injectable, it might not be a good treatment option for people who are afraid of needles.
  • Only available as a brand name, so Apidra (insulin glulisine) can be expensive.
Used for
Dosage forms
  • Injection
  • Inhaler
  • Injection
Price
No pricing information available
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Reviews
57 reviews so far
67%
saidit'sworth it
46%
saiditworked well
11%
saidit'sa big hassle

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Side effects
The Humulin (Human Insulin) FDA package insert doesn’t have numbers about how common side effects are.
1possible side effects
  • Common cold
    11%
See more detailed side effects
Risks and risk factors
  • Changes in blood sugar
  • Changes in skin appearance
  • Weight gain
See more detailed risks and warnings
  • Sharing of pen and needles
  • Low blood sugar
    • Changes in diet and exercise
    • Drinking alcohol
    • Taking other medications for diabetes
    • Over age 65
    • Liver or kidney problems
  • Severe allergic reactions
  • Low blood potassium levels
    • Taking laxatives
    • Taking medications that increase urination
  • Mixing of insulins
  • Fluid buildup
    • Taking Avandia or Actos
See more detailed risks and warnings