Compare Human Insulin vs. Janumet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Humulin
(human insulin)

Janumet
(sitagliptin / metformin)

Lowers blood sugar. This form of insulin is one of the few medications in its class that you can get without a prescription, but it's expensive.Lowers your blood sugar. Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.95Human Insulin
Reviews for Human Insulin
67%
of people (All ages) say Human Insulin is worth it
46%
say it works well
11%
say it's a big hassle
Have you used Humulin (human insulin)?
Worth itNot sureNot worth it
Reviews for Janumet
46%
+21% better vs. Human Insulin
38%
+8% better vs. Human Insulin
15%
+4% better vs. Human Insulin
Have you used Janumet (sitagliptin / metformin)?
Worth itNot sureNot worth it
Side effects
Human InsulinJanumet

The Human Insulin FDA package insert doesn’t have numbers about how common side effects are.

More about Human Insulin side effects »
  • Low blood sugar 15%
  • Diarrhea 4%
  • Ear, nose, or throat infection 1%
  • Headache 3%
More Janumet side effects »
How it works
Human InsulinJanumet
Insulin is a hormone normally produced by your pancreas. It helps your body absorb and store sugar and fat from your bloodstream.Janumet (sitagliptin / metformin) is a combination of two anti-diabetic medicines. Metformin lowers the amount of sugar your body produces, and sitagliptin enhances the release of insulin.
Type of medication
Human InsulinJanumet
Prescription onlyPrescription only
Available as
Human InsulinJanumet
  • Injection
  • Inhaler
  • Pill
  • Extended release
Used for
Human InsulinJanumet
Risk factors for serious side effects
Human InsulinJanumet
    Detailed Humulin (human insulin) risks & warnings »
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    Detailed Janumet (sitagliptin / metformin) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Food
    Human InsulinJanumet
    No food related info.
    • Take with food to avoid upset stomach with diarrhea, nausea, and vomiting.
    Kidneys and liver
    Human InsulinJanumet
    No kidneys and liver related info.
    • Not appropriate for those with poor kidney function.
    Weight
    Human InsulinJanumet
    • People on Humulin (Human Insulin) can experience weight gain. Talk to your doctor or dietitian about changing your diet if this bothers you.
    No weight related info.
    Upsides and benefits
    Human InsulinJanumet
    • Some types of this medication are available without a prescription.
    • Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose.
    • Available in different combinations so that you can do one shot or multiple shots a day.
    • This 2-in-1 combination can lower the number of pills you have to take daily.
    • Lowers A1c (average blood sugar over time) up to 2.5%.
    • Available in extended and immediate release forms to allow better control of your blood sugar.
    • Doesn't increase your appetite unlike other anti-diabetic medicines.
    • Does not cause hypoglycemia or very low blood sugar.
    Downsides and risks
    Human InsulinJanumet
    • Has to be taken exactly as directed or it can cause high or low blood sugar.
    • As with all insulins, you have to work with your doctor closely to make sure you're giving yourself the correct dose, or you can have low or high blood sugar.
    • Available as brand name only and may be expensive.
    • Metformin component usually causes upset stomach.
    • Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
    • Not appropriate for those with poor kidney function.
    Tips from our pharmacists for people taking the medication
    Human InsulinJanumet
    • Change the location where you give yourself the shot every time.
    • Don't use if the liquid in the vial looks different than normal.
    • Store the unopened vials in the refrigerator. The used vials can be kept at room temperature for up to 28 days.
    • Take the medication exactly how your doctor tells you to.
    • Know the symptoms of low blood sugar.
    • Take with food to avoid upset stomach with diarrhea, nausea, and vomiting.
    • May cause headaches and cold-like symptoms.
    • Tell your doctor about any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain.
    • Can be expensive depending on insurance coverage.
    • Check your blood sugar regularly.
    Learn more
    More about Human InsulinSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Humulin (human insulin)?
    Worth itNot sureNot worth it
    More about JanumetSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Janumet (sitagliptin / metformin)?
    Worth itNot sureNot worth it