Compare Humira vs. Imbruvica

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Humira
(adalimumab)

Imbruvica
(ibrutinib)

Calms down the immune system. Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.Coming soon.
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Coupons for Humira
Best available price for 1 (2 pens of 40mg/0.8ml) carton of adalimumab
Coupons for Imbruvica
Best available price for 1 (90 capsules of 140mg) bottle of ibrutinib
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.94Humira
Reviews for Humira (adalimumab)
60%
of people (All ages) say Humira (adalimumab) is worth it
51%
say it works well
26%
say it's a big hassle
182 reviews
Have you used Humira (adalimumab)?
Worth itNot sureNot worth it
Reviews for Imbruvica (ibrutinib)
Not enough review data. Review it!
+40% better vs. Humira (adalimumab)
Not enough review data. Review it!
+32% better vs. Humira (adalimumab)
Not enough review data. Review it!
+26% better vs. Humira (adalimumab)
Have you used Imbruvica (ibrutinib)?
Worth itNot sureNot worth it
Side effects
HumiraImbruvica
  • Upper airway infection 4%
  • Rash 6%
  • Headache 4%
  • Sinus infection 2%
  • Nausea 1%
  • Injection site reactions 7%
  • Urinary tract infection 3%
  • Flu syndrome 1%
  • Stomach pain 3%
  • High cholesterol 2%
More Humira side effects »

We haven’t found good data for Imbruvica side effects.

FDA side effect reports for Imbruvica »
How it works
HumiraImbruvica
Humira (adalimumab) is a TNF blocker which stops inflammation.Coming soon.
Type of medication
HumiraImbruvica
Prescription only
Available as
HumiraImbruvica
  • Injection
  • Pill
Used for
HumiraImbruvica
  • Chronic Lymphoid Leukemia
Risk factors for serious side effects
HumiraImbruvica
  • Taking other immunosuppressant medications such as Kineret or Orencia
  • Age 65 or older
  • Active, chronic, or recurrent infection
  • Comorbidities
  • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
Detailed Humira (adalimumab) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Upsides and benefits
    HumiraImbruvica
    • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
    • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
    • Humira (adalimumab) treats many different autoimmune conditions.
    • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
    Coming soon
    Downsides and risks
    HumiraImbruvica
    • Not first-choice treatment for rheumatoid arthritis.
    • Humira (adalimumab) is an injection and not an oral medication.
    • Humira (adalimumab) is expensive because there's no generic available yet.
    • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
    • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
    • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
    Coming soon
    Tips from our pharmacists for people taking the medication
    HumiraImbruvica
    • Humira (adalimumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so on your own.
    • Humira (adalimumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
    • Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
    • Each time you use Humira (adalimumab), it's important to rotate the sites you chose to inject it in. Don't inject Humira (adalimumab) into skin that's red, bruised, or irritated.
    • As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container, and not in the trash.
    Coming soon
    Learn more
    More about HumiraSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Humira (adalimumab)?
    Worth itNot sureNot worth it
    More about ImbruvicaSide effectsReviews & ratingsFDA package insert
    Have you used Imbruvica (ibrutinib)?
    Worth itNot sureNot worth it