› Although rare, Remicade (infliximab) can hurt your liver. If you have appetite/weight loss, stomach discomfort, vomiting, or dark urine, talk to your doctor. If you have yellowing of skin/eyes, talk to your doctor right away.
Upsides and benefits
› Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
› You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
› Humira (adalimumab) treats many different autoimmune conditions.
› Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
› People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
› People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
› Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
› After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
› Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
Downsides and risks
› Not first-choice treatment for rheumatoid arthritis.
› Humira (adalimumab) is an injection and not an oral medication.
› Humira (adalimumab) is expensive because there's no generic available yet.
› Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
› You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
› Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
› You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
› Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
› Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
› In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
› No generic available, so it can be costly.
Tips from our pharmacists for people taking the medication
› Humira (adalimumab) is a medication that's injected under the skin. Your doctor can give you your first dose, then you can inject yourself at home once you feel comfortable doing so on your own.
› Humira (adalimumab) lowers your ability to fight infections, so it's important to let your doctor know if you have a fever, cough, or flu-like symptoms.
› Tell your doctor if you have an allergy to latex since the syringe needle cover has latex in it.
› Each time you use Humira (adalimumab), it's important to rotate the sites you chose to inject it in. Don't inject Humira (adalimumab) into skin that's red, bruised, or irritated.
› As with all injection medicines, store securely away from children and throw away used syringes in an FDA-approved sharps disposal container, and not in the trash.
› Remicade (infliximab) can in some cases cause a serious allergic reaction either immediately or several days after the treatment. Your doctor can give you medicines that will lower this risk.
› Your doctor will test you for tuberculosis before taking Remicade (infliximab) and regularly during treatment.
› Remicade (infliximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, cough, or flu-like symptoms.
› You should not receive any live vaccines while taking Remicade (infliximab). Tell your doctor that you are taking Remicade (infliximab) before receiving any vaccines.
› If you have any signs or new or worsening symptoms such as heart, neurological, or autoimmune conditions, talk to your doctor. Tell your doctor about symptoms such as bruising or bleeding.