Compare hydrochlorothiazide vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Microzide (hydrochlorothiazide)

Prescription only

Coreg (Carvedilol)

Prescription only
Removes water from the body, which lowers blood pressure.

Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.

4.5/ 7 average rating with 139 reviewsforhydrochlorothiazide
Lowers blood pressure and controls heart rate.

Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.

4.8/ 7 average rating with 406 reviewsforCoreg
Upsides
  • Does a good job getting rid of extra fluids in your body by making you urinate more.
  • A first-choice blood pressure treatment. Works especially well for people of African descent.
  • Lowers the risk of heart attack and stroke.
  • Good option if you have high blood pressure and heart failure.
  • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
  • Can be good for patients with osteoporosis since it raises the body's level of calcium.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
Downsides
  • Makes you urinate more often.
  • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
  • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
  • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
  • You have to take Carvedilol with food.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
Lowest price near you
$4
Find instant savings
Lowest price near you
$4
Find instant savings
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
139 
47%
think this treatment is worth it
31%
think this treatment works well
16%
think this treatment is a hassle

Have you used Microzide (hydrochlorothiazide (HCTZ))?

Leave a review
406 
53%
think this treatment is worth it
46%
think this treatment works well
18%
think this treatment is a hassle

Have you used Coreg (Carvedilol)?

Leave a review
Side effects
The Microzide (hydrochlorothiazide (HCTZ)) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
  • Dizziness
    6%
  • Bradycardia
    2%
  • Postural hypotension
    2%
  • Insomnia
    2%
  • Diarrhea
    2%
See more detailed side effects
Risks and warnings
  • Dehydration and electrolyte imbalance

    Current electrolyte imbalance

    ...and 2 more risk factors

  • Severe allergic reactions

    History of sulfa allergies

  • Gout

    History of gout

    ...and 1 more risk factors

  • Vision problems

    History of sulfa or penicillin allergies

  • Higher blood sugars

    Diabetes

See more detailed risks and warnings
  • Worsened chest pain; increased risk of heart attack and heart rhythm problems

    Abrupt discontinuation of Coreg (Carvedilol)

  • Worsening heart failure

    Congestive heart failure

    ...and 1 more risk factors

  • Masked symptoms of low blood sugar

    Diabetes

  • Increased risks during surgery

    Major surgery requiring anesthesia

See more detailed risks and warnings