Compare Hydrochlorothiazide vs. Dutoprol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Microzide
(Hydrochlorothiazide )

Dutoprol
(Metoprolol Succinate / Hydrochlorothiazide)

Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Lowers blood pressure. Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) helps lower blood pressure by working in two different ways in your body. It's good for stubbornly high blood pressure.
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Reviews & ratings
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4.467153284671533Hydrochlorothiazide
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
of people say Microzide (Hydrochlorothiazide (Hctz)) is worth it
31%
say it works well
15%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
HydrochlorothiazideDutoprol

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »
  • Common cold 2%
  • Fatigue 2%
  • Back pain 1%
More Dutoprol side effects »
How it works
HydrochlorothiazideDutoprol
Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) is a combination medicine that helps control your blood pressure and reduce the risk of a heart attack or stroke. Hydrochlorothiazide is a diuretic that removes extra water from your body. Metoprolol is a beta blocker that lowers your heart rate.
Type of medication
HydrochlorothiazideDutoprol
Antihypertensive
Diuretic
Prescription only
Antihypertensive
Beta blocker
Diuretic
Prescription only
Available as
HydrochlorothiazideDutoprol
  • Pill
  • Pill
Used for (click to learn more)
HydrochlorothiazideDutoprol
Risk factors for serious side effects
HydrochlorothiazideDutoprol
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
    Detailed Microzide (Hydrochlorothiazide (Hctz)) risks & warnings »
    • Sudden discontinuation of medicine
    • History of asthma
    • History of diabetes
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
    • Current electrolyte imbalance
    • History of gout
    • Current kidney problems
    Detailed Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) risks & warnings »
    Pregnancy category
    HydrochlorothiazideDutoprol
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Doesn't work well in people with severe kidney problems.
    • Requires routine blood tests to check kidney function.
    • Check your blood pressure and kidney function 1 week after starting the medicine, then routinely after that.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    HydrochlorothiazideDutoprol
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    • Lowers the risk of heart attack and stroke.
    • Combines the benefits of two blood pressure-lowering medicines in a single pill.
    • Helpful in getting rid of extra fluids in your body.
    • Lowers the risk of heart attack and stroke.
    Downsides and risks
    HydrochlorothiazideDutoprol
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    • Not the first choice to lower blood pressure.
    • Brand only, can be more expensive.
    • Can make you urinate more often and feel out of breath during physical activities, which may not go away.
    • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
    • Forgetting to take the medicine or stopping it suddenly can cause a heart attack.
    Tips from our pharmacists for people taking the medication
    HydrochlorothiazideDutoprol
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    • Makes you urinate more often, so don't take it too close to bedtime.
    • Can make you feel dizzy or short of breath the first few days, but this should improve as your body gets used to the medicine.
    • Check your blood pressure and kidney function 1 week after starting the medicine, then routinely after that.
    • Tell your doctor about any cold-like symptoms, dizziness, headache, fatigue, or muscle weakness that doesn't go away.
    • Don't stop taking this medicine suddenly since it can trigger heart problems.
    Learn more
    More about HydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    More about DutoprolSide effectsReviews & ratingsAlternativesFDA package insert