Compare Hydrochlorothiazide vs. Edecrin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Microzide
(Hydrochlorothiazide )

Edecrin
(Ethacrynic Acid)

Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.
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Reviews & ratings
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4.467153284671533Hydrochlorothiazide
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
of people (All ages) say Microzide (Hydrochlorothiazide (Hctz)) is worth it
31%
say it works well
15%
say it's a big hassle
137 reviews
Have you used Microzide (Hydrochlorothiazide (Hctz))?
Worth itNot sureNot worth it

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Have you used Edecrin (Ethacrynic Acid)?
Worth itNot sureNot worth it
Side effects
HydrochlorothiazideEdecrin

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

We haven’t found good data for Edecrin side effects.

FDA side effect reports for Edecrin »
How it works
HydrochlorothiazideEdecrin
Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Coming soon.
Type of medication
HydrochlorothiazideEdecrin
Antihypertensive
Diuretic
Prescription only
Coming soon.
Available as
HydrochlorothiazideEdecrin
  • Pill
  • Pill
Used for (click to learn more)
HydrochlorothiazideEdecrin
  • Edema
Risk factors for serious side effects
HydrochlorothiazideEdecrin
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
    Detailed Microzide (Hydrochlorothiazide (Hctz)) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Kidneys and liver
    HydrochlorothiazideEdecrin
    • Requires routine blood tests to check kidney function.
    No kidneys and liver related info.
    Upsides and benefits
    HydrochlorothiazideEdecrin
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    Coming soon
    Downsides and risks
    HydrochlorothiazideEdecrin
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    Coming soon
    Tips from our pharmacists for people taking the medication
    HydrochlorothiazideEdecrin
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    Coming soon
    Learn more
    More about HydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Microzide (Hydrochlorothiazide (Hctz))?
    Worth itNot sureNot worth it
    More about EdecrinSide effectsFDA package insert
    Have you used Edecrin (Ethacrynic Acid)?
    Worth itNot sureNot worth it