Compare Hydrochlorothiazide vs. triamterene

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Microzide
(Hydrochlorothiazide )

Dyrenium
(Triamterene)

Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.
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Reviews & ratings
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4.467153284671533Hydrochlorothiazide
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
of people (All ages) say Microzide (Hydrochlorothiazide (Hctz)) is worth it
31%
say it works well
15%
say it's a big hassle
137 reviews
Have you used Microzide (Hydrochlorothiazide (Hctz))?
Worth itNot sureNot worth it

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Have you used Dyrenium (Triamterene)?
Worth itNot sureNot worth it
Side effects
Hydrochlorothiazidetriamterene

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

We haven’t found good data for triamterene side effects.

FDA side effect reports for triamterene »
How it works
Hydrochlorothiazidetriamterene
Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Coming soon.
Type of medication
Hydrochlorothiazidetriamterene
Antihypertensive
Diuretic
Prescription only
Coming soon.
Available as
Hydrochlorothiazidetriamterene
  • Pill
  • Pill
Used for (click to learn more)
Hydrochlorothiazidetriamterene
  • Edema
Risk factors for serious side effects
Hydrochlorothiazidetriamterene
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
    Detailed Microzide (Hydrochlorothiazide (Hctz)) risks & warnings »
    Coming soon.
    Pregnancy category
    Hydrochlorothiazidetriamterene
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Kidneys and liver
    • Doesn't work well in people with severe kidney problems.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver related info.
    Upsides and benefits
    Hydrochlorothiazidetriamterene
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    Coming soon.
    Downsides and risks
    Hydrochlorothiazidetriamterene
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    Hydrochlorothiazidetriamterene
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    Coming soon.
    Learn more
    More about HydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Microzide (Hydrochlorothiazide (Hctz))?
    Worth itNot sureNot worth it
    More about triamtereneSide effectsFDA package insert
    Have you used Dyrenium (Triamterene)?
    Worth itNot sureNot worth it