Compare Hydrochlorothiazide vs. Ziac

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Microzide
(Hydrochlorothiazide )

Ziac
(Bisoprolol / Hydrochlorothiazide)

Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.
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Reviews & ratings
Button Group. All currently active
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4.467153284671533Hydrochlorothiazide
Reviews for Microzide (Hydrochlorothiazide (Hctz))
47%
of people say Microzide (Hydrochlorothiazide (Hctz)) is worth it
31%
say it works well
15%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
HydrochlorothiazideZiac

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

We haven’t found good data for Ziac side effects.

FDA side effect reports for Ziac »
How it works
HydrochlorothiazideZiac
Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Coming soon.
Type of medication
HydrochlorothiazideZiac
Antihypertensive
Diuretic
Prescription only
Coming soon.
Available as
HydrochlorothiazideZiac
  • Pill
  • Pill
Used for (click to learn more)
HydrochlorothiazideZiac
  • Hypertension
Risk factors for serious side effects
HydrochlorothiazideZiac
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
    Detailed Microzide (Hydrochlorothiazide (Hctz)) risks & warnings »
    Coming soon.
    Pregnancy category
    HydrochlorothiazideZiac
    BFDA pregnancy category (Probably safe)

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • Doesn't work well in people with severe kidney problems.
    • Requires routine blood tests to check kidney function.
    No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    HydrochlorothiazideZiac
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    Coming soon.
    Downsides and risks
    HydrochlorothiazideZiac
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    HydrochlorothiazideZiac
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    Coming soon.
    Learn more
    More about HydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    More about ZiacSide effectsReviews & ratingsFDA package insert