Compare Hydrochlorothiazide vs. Ziac

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Microzide
(hydrochlorothiazide )

Ziac
(bisoprolol / hydrochlorothiazide)

Lowers blood pressure. Removes extra water from your body. Microzide (Hydrochlorothiazide (Hctz)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.Coming soon.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
No pricing data for this drug at this filter setting. Try searching onGoodRx
No pricing data for this drug at this filter setting. Try searching onGoodRx
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.48Hydrochlorothiazide
Reviews for Microzide (hydrochlorothiazide )
47%
of people (All ages) say Microzide (hydrochlorothiazide ) is worth it
31%
say it works well
16%
say it's a big hassle
139 reviews
Have you used Microzide (hydrochlorothiazide )?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Ziac (bisoprolol / hydrochlorothiazide)?
Worth itNot sureNot worth it
Side effects
HydrochlorothiazideZiac

The Hydrochlorothiazide FDA package insert doesn’t have numbers about how common side effects are.

More about Hydrochlorothiazide side effects »

We haven’t found good data for Ziac side effects.

FDA side effect reports for Ziac »
How it works
HydrochlorothiazideZiac
Microzide (Hydrochlorothiazide (Hctz)) is a thiazide diuretic (water pill). It works in the kidneys to make you urinate more, which removes extra water and certain electrolytes. This lowers blood pressure and swelling.Coming soon.
Type of medication
HydrochlorothiazideZiac
Prescription only
Available as
HydrochlorothiazideZiac
  • Pill
  • Pill
Used for
HydrochlorothiazideZiac
  • Hypertension
Risk factors for serious side effects
HydrochlorothiazideZiac
  • Current electrolyte imbalance
  • History of sulfa allergies
  • History of gout
  • Current kidney problems
    Detailed Microzide (hydrochlorothiazide ) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Kidneys and liver
    HydrochlorothiazideZiac
    • Requires routine blood tests to check kidney function.
    No kidneys and liver related info.
    Upsides and benefits
    HydrochlorothiazideZiac
    • Works well to get rid of extra fluids in your body through urination.
    • A first-choice blood pressure treatment for many people. Works especially well for African Americans.
    • Lowers the risk of heart attack and stroke.
    • Good option if you have both high blood pressure and heart failure.
    • Raises calcium levels in the body, so it can be good for people with osteoporosis to slow down bone loss and even help with new bone formation.
    • Most people have very few side effects.
    Coming soon
    Downsides and risks
    HydrochlorothiazideZiac
    • Makes you urinate more often.
    • Doesn't work well in people with severe kidney problems.
    Coming soon
    Tips from our pharmacists for people taking the medication
    HydrochlorothiazideZiac
    • Starts working in about 2 hours.
    • Makes you urinate more often, so avoid taking it at bedtime.
    • Can cause dizziness in the first few days.
    • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
    • Tell your doctor about any dizziness, fatigue, or muscle weakness that doesn't go away.
    • Requires routine blood tests to check kidney function.
    Coming soon
    Learn more
    More about HydrochlorothiazideSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Microzide (hydrochlorothiazide )?
    Worth itNot sureNot worth it
    More about ZiacSide effectsReviews & ratingsFDA package insert
    Have you used Ziac (bisoprolol / hydrochlorothiazide)?
    Worth itNot sureNot worth it