Compare ibuprofen vs. Aspirin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil (ibuprofen)

Over-the-counter

Aspirin

Over-the-counter
Relieves pain, fever, and swelling.

Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.

5.5/ 7 average rating with 892 reviewsforibuprofen
Relieves pain, fever, and inflammation. Protects your heart and thins blood.

A low dose of Aspirin (81mg) every day can protect your heart, but it's not the best medicine to take for pain, swelling, or fever.

5.2/ 7 average rating with 533 reviewsforAspirin
Upsides
  • Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
  • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
  • Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
  • Advil (ibuprofen) causes less stomach problems than its alternatives.
  • It comes in different flavored liquid forms that makes it easy for children to take.
  • When taking low doses (81 mg) every day, Aspirin provides protection for your heart and prevents heart attacks and stroke.
  • Used in higher doses to relieve pain, swelling, and fever.
  • Available over-the-counter in drugstores by itself and in combination with other cold and flu medications.
Downsides
  • Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
  • It needs to be taken with food or millk to avoid getting an upset stomach.
  • Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
  • Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
  • Not a preferred medication for treating pain, swelling, or fever due to its high risk of bleeding.
  • NSAIDs (like ibuprofen and naproxen) and acetaminophen (Tylenol) are better for treating pain and fever thank Aspirin.
  • Aspirin raises your risk of bleeding, especially when used with other blood thinner medications like warfarin (Coumadin).
  • Studies show that using higher doses of Aspirin (162 mg or more) every day raises your risk of stomach bleeding and doesn't provide any additional heart protection.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Suspension
  • Pill
Price
Lowest price near you
$7.14
Find instant savings
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
892 
88%
think this treatment is worth it
52%
think this treatment works well
4%
think this treatment is a hassle

Have you used Advil (ibuprofen)?

Leave a review
533 
76%
think this treatment is worth it
41%
think this treatment works well
6%
think this treatment is a hassle

Have you used Aspirin?

Leave a review
Side effects
The Advil (ibuprofen) FDA package insert doesn’t have numbers about how common side effects are.
The Aspirin FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack and stroke

    History of heart problems

    ...and 1 more risk factors

  • Stomach bleeding

    History of stomach bleeding

    ...and 5 more risk factors

  • Severe allergic reaction

    Asthma

    ...and 3 more risk factors

  • Kidney damage

    Kidney disease

    ...and 5 more risk factors

  • Harm to fetus (unborn baby)

    Women who want to or can become pregnant

    ...and 1 more risk factors

See more detailed risks and warnings
  • Brain damage or death from Reye's Syndrome

    Children 18 years or younger

    ...and 1 more risk factors

  • Stomach bleeding

    History of stomach bleeding or ulcers

    ...and 3 more risk factors

  • Serious allergic reactions

    Asthma

    ...and 4 more risk factors

  • Harm to unborn babies

    Women of childbearing age

See more detailed risks and warnings