Compare ibuprofen vs. Coumadin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil
(ibuprofen)

Coumadin
(warfarin)

Relieves pain, fever, and swelling. Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.Prevents blood clots. Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.
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Coupons for ibuprofen
Best available price for 90 (800mg) tablets of ibuprofen
Coupons for Coumadin
Best available price for 30 (5mg) tablets of warfarin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.49ibuprofen
Reviews for ibuprofen
88%
of people (All ages) say ibuprofen is worth it
52%
say it works well
4%
say it's a big hassle
892 reviews
Have you used Advil (ibuprofen)?
Worth itNot sureNot worth it
Reviews for Coumadin
61%
+27% better vs. ibuprofen
54%
-2% worse vs. ibuprofen
21%
+17% better vs. ibuprofen
513 reviews
Have you used Coumadin (warfarin)?
Worth itNot sureNot worth it
Side effects
ibuprofenCoumadin

The ibuprofen FDA package insert doesn’t have numbers about how common side effects are.

More about ibuprofen side effects »

The Coumadin FDA package insert doesn’t have numbers about how common side effects are.

More about Coumadin side effects »
How it works
ibuprofenCoumadin
Advil (ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). It stops the inflammation process in your body, which relieves pain, swelling, and fever.Coumadin (warfarin) prevents blood clots from forming. It doesn't break up clots that already exist. It can only stop new ones from forming or old ones from getting bigger.
Type of medication
ibuprofenCoumadin
Over-the-counterPrescription only
Available as
ibuprofenCoumadin
  • Pill
  • Chewable tablet
  • Suspension
  • Pill
Used for
ibuprofenCoumadin
Risk factors for serious side effects
ibuprofenCoumadin
  • History of heart problems
  • Taking Advil (ibuprofen) for a long period of time
  • History of stomach bleeding
  • Age 60 or older
  • Taking aspirin, other NSAIDs, or blood thinners
Detailed Advil (ibuprofen) risks & warnings »
  • Coumadin (warfarin) dose too high
  • Age greater than 65 year
  • History of stomach bleeding
  • High blood pressure
  • Kidney or liver problems
Detailed Coumadin (warfarin) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Interactions
ibuprofenCoumadin
No interactions related info.
  • Coumadin (warfarin) interacts with many drugs and supplements. This can increase your risk of bleeding or of developing a new blood clot. If you start a new medication or change your diet, let your doctor know so they can change your dose if necessary.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
Food
ibuprofenCoumadin
  • Take it with food or milk to prevent stomach upset.
  • It needs to be taken with food or millk to avoid getting an upset stomach.
No food related info.
Kidneys and liver
ibuprofenCoumadin
  • Advil (ibuprofen) can damage your kidneys. Taking the lowest dose for the shortest amount of time lowers your risk. Talk to your doctor if this worries you, or if you already have kidney damage before you start taking Advil (ibuprofen).
No kidneys and liver related info.
Pain
ibuprofenCoumadin
  • Do not take for more than 10 days for pain relief or more than 3 days for fever. Talk to your doctor if your symptoms do not go away.
  • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
No pain related info.
Upsides and benefits
ibuprofenCoumadin
  • Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
  • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
  • Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
  • Advil (ibuprofen) causes less stomach problems than its alternatives.
  • It comes in different flavored liquid forms that makes it easy for children to take.
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
Downsides and risks
ibuprofenCoumadin
  • Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
  • It needs to be taken with food or millk to avoid getting an upset stomach.
  • Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
  • Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
Tips from our pharmacists for people taking the medication
ibuprofenCoumadin
  • Starts working in about 30 to 60 minutes.
  • Take it with food or milk to prevent stomach upset.
  • Do not take for more than 10 days for pain relief or more than 3 days for fever. Talk to your doctor if your symptoms do not go away.
  • If you normally take a daily aspirin, make sure to take Advil (ibuprofen) at least 30 minutes after taking aspirin or more than 8 hours before taking aspirin. This will help make sure the aspirin still works in your body.
  • Advil (ibuprofen) increases the risk of stomach bleeding so tell your doctor right away if you experience any bleeding.
  • If you are allergic to aspirin, there is a chance you may be allergic to Advil (ibuprofen) as well.
  • Prevents clots from forming or getting bigger. It doesn't break up clots that already exist.
  • Take Coumadin (warfarin) exactly as your doctor tells you.
  • Once you're taking Coumadin (warfarin), it'll take longer for your body to heal if you get cut or bruised. Call your doctor if you notice any unusual bleeding or bruising.
  • Carry a list of your medications with you or wear a medical bracelet that says you're on Coumadin (warfarin) in case you have a medical emergency.
  • Your doctor will check your blood regularly for the first few months that you're taking Coumadin (warfarin).
  • To get the best results, don't fall behind on taking your other medicines and eat the same amount of vegetables each day.
Learn more
More about ibuprofenSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Advil (ibuprofen)?
Worth itNot sureNot worth it
More about CoumadinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coumadin (warfarin)?
Worth itNot sureNot worth it