Compare ibuprofen vs. Coumadin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil (ibuprofen)

Over-the-counter

Coumadin (warfarin)

Prescription only
Relieves pain, fever, and swelling.

Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.

5.5/ 7 average rating with 892 reviewsforibuprofen
Prevents blood clots.

Coumadin (warfarin) is a cheap and effective medicine that prevents new blood clots. It requires regular blood tests and you'll need to eat, exercise, and take your medicines consistently.

5.2/ 7 average rating with 513 reviewsforCoumadin
Upsides
  • Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
  • Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
  • Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
  • Advil (ibuprofen) causes less stomach problems than its alternatives.
  • It comes in different flavored liquid forms that makes it easy for children to take.
  • Coumadin (warfarin) is available as a generic, so it should be less expensive than the brand version.
  • In case you start bleeding too much while using Coumadin (warfarin), your doctor can give you another drug that reverses Coumadin (warfarin)'s effects.
  • Coumadin (warfarin) comes in numerous strengths.
  • Coumadin (warfarin) has been around for a long time and is one of the most commonly used 'blood thinner' medicines.
Downsides
  • Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
  • It needs to be taken with food or millk to avoid getting an upset stomach.
  • Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
  • Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
  • Raises your risk of bleeding and bruising.
  • Requires regular blood work, such as an INR, to make sure Coumadin (warfarin) is working correctly.
  • Your daily dose of Coumadin (warfarin) can change if you change your diet, exercise patterns, or use of alcohol.
  • A lot of other drugs and supplements interact with Coumadin (warfarin), so you'll need to check with your doctor or pharmacist before starting any new medicines.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Suspension
  • Pill
Price
Lowest price near you
$7.14
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$4
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Reviews
892 
88%
think this treatment is worth it
52%
think this treatment works well
4%
think this treatment is a hassle

Have you used Advil (ibuprofen)?

Leave a review
513 
61%
think this treatment is worth it
54%
think this treatment works well
21%
think this treatment is a hassle

Have you used Coumadin (warfarin)?

Leave a review
Side effects
The Advil (ibuprofen) FDA package insert doesn’t have numbers about how common side effects are.
The Coumadin (warfarin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Heart attack and stroke

    History of heart problems

    ...and 1 more risk factors

  • Stomach bleeding

    History of stomach bleeding

    ...and 5 more risk factors

  • Severe allergic reaction

    Asthma

    ...and 3 more risk factors

  • Kidney damage

    Kidney disease

    ...and 5 more risk factors

  • Harm to fetus (unborn baby)

    Women who want to or can become pregnant

    ...and 1 more risk factors

See more detailed risks and warnings
  • Life threatening bleeding

    Coumadin (warfarin) dose too high

    ...and 8 more risk factors

  • Harm to fetus

    Women of childbearing age

See more detailed risks and warnings