Compare Ibuprofen vs. Lodine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil
(Ibuprofen)

Lodine
(Etodolac)

Relieves pain, fever, and inflammation. Advil (Ibuprofen) works well for mild to moderate pain and inflammation, but it doesn't last as long as other NSAIDs.Coming soon.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.49Ibuprofen
Reviews for Advil (Ibuprofen)
88%
of people (All ages) say Advil (Ibuprofen) is worth it
52%
say it works well
4%
say it's a big hassle
892 reviews
Have you used Advil (Ibuprofen)?
Worth itNot sureNot worth it

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Have you used Lodine (Etodolac)?
Worth itNot sureNot worth it
Side effects
IbuprofenLodine

We haven’t found good data for Ibuprofen side effects.

FDA side effect reports for Ibuprofen »

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »
How it works
IbuprofenLodine
Advil (Ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Coming soon.
Type of medication
IbuprofenLodine
Prescription or OTC
Available as
IbuprofenLodine
  • Pill
  • Chewable tablet
  • Oral suspension
  • Pill
  • Extended release
Used for
IbuprofenLodine
  • Juvenile Rheumatoid Arthritis Osteoarthritis Pain Rheumatoid Arthritis
Risk factors for serious side effects
IbuprofenLodine
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Smoking
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Hemophilia
  • von Willebrand's disease
  • Low blood platelet count
  • Taking anticoagulant medications
  • Asthma
  • Rhinitis
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • Women of childbearing age
Detailed Advil (Ibuprofen) risks & warnings »
Coming soon.
Pregnancy

Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
IbuprofenLodine
  • It needs to be taken with food to avoid getting an upset stomach.
  • Take it with a meal or a snack to prevent upset stomach.
No food related info.
Kidneys and liver
IbuprofenLodine
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
  • Advil (Ibuprofen) is an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil (Ibuprofen) for any amount of time.
No kidneys and liver related info.
Pain
IbuprofenLodine
  • Works well to relieve pain, swelling, and fevers.
  • Starts relieving pain in 30 to 60 minutes.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
No pain related info.
Upsides and benefits
IbuprofenLodine
  • Works well to relieve pain, swelling, and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Ibuprofen works as well as aspirin in treating pain and causes fewer stomach problems.
  • Ibuprofen works better than acetaminophen (Tylenol) at lowering fever and relieving sinus pain.
  • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
Coming soon
Downsides and risks
IbuprofenLodine
  • Ibuprofen doesn't work as long as other NSAIDs, so follow the package directions on how often you can take it.
  • It needs to be taken with food to avoid getting an upset stomach.
  • Can't be taken by pregnant women.
  • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
  • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
Coming soon
Tips from our pharmacists for people taking the medication
IbuprofenLodine
  • Starts relieving pain in 30 to 60 minutes.
  • Take it with a meal or a snack to prevent upset stomach.
  • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
  • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
  • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
Coming soon
Learn more
More about IbuprofenSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Advil (Ibuprofen)?
Worth itNot sureNot worth it
More about LodineSide effectsReviews & ratingsFDA package insert
Have you used Lodine (Etodolac)?
Worth itNot sureNot worth it