Compare Ibuprofen vs. Norco

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Advil
(Ibuprofen)

Norco
(Hydrocodone / Acetaminophen)

Relieves pain, fever, and inflammation. Advil (Ibuprofen) works well for mild to moderate pain and inflammation, but it doesn't last as long as other NSAIDs.Treats moderate to severe pain. Norco (Hydrocodone / Acetaminophen) is a good option to treat pain as needed when over-the-counter medicines can't control the symptoms, but must make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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Reviews & ratings
Button Group. All currently active
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5.479768786127168Ibuprofen
Reviews for Advil (Ibuprofen)
88%
of people say Advil (Ibuprofen) is worth it
51%
say it works well
4%
say it's a big hassle
Reviews for Norco (Hydrocodone / Acetaminophen)
67%
21% vs. Advil (Ibuprofen)
44%
7% vs. Advil (Ibuprofen)
13%
9% vs. Advil (Ibuprofen)
Side effects
IbuprofenNorco

We haven’t found good data for Ibuprofen side effects.

FDA side effect reports for Ibuprofen »

The Norco FDA package insert doesn’t have numbers about how common side effects are.

More about Norco side effects »
How it works
IbuprofenNorco
Advil (Ibuprofen) is a non-steroidal anti-inflammatory drug (NSAID). It blocks the inflammation process in your body, which relieves swelling and pain.Norco (Hydrocodone / Acetaminophen) is a combination pain medicine. Hydrocodone is an opioid (similar to morphine) that works in the brain to lower pain perception. Acetaminophen is a non-opioid pain reliever and fever reducer.
Type of medication
IbuprofenNorco
Pain reliever
Nonsteroidal anti-inflammatory drug (NSAID)
Prescription or OTC
Pain reliever
Opioid
Acetaminophen (APAP)
Prescription only
Available as
IbuprofenNorco
  • Pill
  • Chewable tablet
  • Oral suspension
  • Pill
  • Oral solution
Used for (click to learn more)
IbuprofenNorco
Risk factors for serious side effects
IbuprofenNorco
  • History of heart problems
  • High blood pressure
  • High cholesterol
  • Diabetes
  • Smoking
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Hemophilia
  • von Willebrand's disease
  • Low blood platelet count
  • Taking anticoagulant medications
  • Asthma
  • Rhinitis
  • Nasal polyps
  • Aspirin allergy
  • NSAID allergy
  • Kidney disease
  • Heart failure
  • Liver disease
  • Taking high blood pressure medications
  • Age 65 years or older
  • Women of childbearing age
Detailed Advil (Ibuprofen) risks & warnings »
  • Current liver disease
  • Taking with alcohol
  • Taking other medicines with acetaminophen
  • Age 65 or greater
  • Higher dose
  • People with not enough thyroid hormones
  • History of lung problems
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
    • Long-term use of opioids in mother
    • Breastfeeding while taking Norco (Hydrocodone / Acetaminophen)
    • Taking more than the prescribed dose
    • Long-term use
    • History of drug abuse
    Detailed Norco (Hydrocodone / Acetaminophen) risks & warnings »
    Pregnancy category
    IbuprofenNorco
    DFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.
    • Avoid alcohol.
    Food
    • It needs to be taken with food to avoid getting an upset stomach.
    • Take it with a meal or a snack to prevent upset stomach.
    • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
    • Take it with food to lower the chance of an upset stomach.
    Kidneys and liver
    • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • Advil (Ibuprofen) is an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil (Ibuprofen) for any amount of time.
    No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.
    • Dizziness and drowsiness is common.
    • Can make you dizzy or drowsy. Avoid activities need you to be fully alert until you know how it affects you.
    Weight
    No specific weight-related info.
    • Hydrocodone, one of the medications in Norco (Hydrocodone / Acetaminophen) passes into breast milk. Women with a history of long-term opioid use increase the risk of neonatal withdrawal syndrome. Symptoms in the newborn include irritability, vomiting, diarrhea, tremor and lack of weight gain. Opioid withdrawal in infants is a life-threatening emergency and needs medical help right away.
    Upsides and benefits
    IbuprofenNorco
    • Works well to relieve pain, swelling, and fevers.
    • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
    • Ibuprofen works as well as aspirin in treating pain and causes fewer stomach problems.
    • Ibuprofen works better than acetaminophen (Tylenol) at lowering fever and relieving sinus pain.
    • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
    • Combination pain medicine with an opiod component (hydrocodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
    • Provides quick relief for moderate to severe pain to improve quality of life.
    • Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
    • Generally well tolerated by people, especially if taken with food to lower risk of stomach upset.
    • Lower rates of misuse compared to pure opioid medicines.
    • Can help you fall asleep easier.
    Downsides and risks
    IbuprofenNorco
    • Ibuprofen doesn't work as long as other NSAIDs, so follow the package directions on how often you can take it.
    • It needs to be taken with food to avoid getting an upset stomach.
    • Can't be taken by pregnant women.
    • It can cause serious kidney and stomach problems (like ulcers and bleeding) the longer you take it.
    • Like all NSAIDs, it can raise your risk of having blood clots, heart attack, or stroke.
    • Dizziness and drowsiness is common.
    • Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Norco if you need.
    • All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
    • The non-opioid part of Norco, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
    • Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
    • Avoid alcohol.
    Tips from our pharmacists for people taking the medication
    IbuprofenNorco
    • Starts relieving pain in 30 to 60 minutes.
    • Take it with a meal or a snack to prevent upset stomach.
    • Can make you bruise or bleed more easily and it can also cause stomach ulcers.
    • Don't take it with other blood thinners, like aspirin, unless your doctor tells you it's safe.
    • Can hurt your kidneys, so don't use it if you have a history of kidney problems.
    • This is a combination pain medication. It contains both an opioid medicine and acetaminophen (Tylenol).
    • Works best if you take it as soon as you start feeling pain. Starts working in 30 minutes and pain relief lasts 4 to 6 hours.
    • Can make you dizzy or drowsy. Avoid activities need you to be fully alert until you know how it affects you.
    • Take it with food to lower the chance of an upset stomach.
    • Constipation is common and may not go away while you're taking this medicine. Drinking lots of water and using laxatives can help.
    • Don't take more than instructed to prevent liver damage.
    • Use it for the shortest time and at the lowest dose possible, to lower your chance of becoming addicted.
    • Talk to your doctor if it doesn't work well enough to relieve your pain, or if the side effects are really bad.
    Learn more
    More about IbuprofenSide effectsReviews & ratingsAlternativesFDA package insert
    More about NorcoSide effectsReviews & ratingsAlternativesFDA package insert