Compare Imbruvica vs. Orencia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Imbruvica (Ibrutinib)

Orencia (abatacept)

Prescription only
No information currently available
Calms down the immune system and prevents joint damage.

Orencia (abatacept) slows the progress of rheumatoid arthritis, but can also cause serious side effects.

Upsides
No information currently available
  • In a 2-year study that used IV Orencia (abatacept) with methotrexate, more than half of the people had remission and the majority felt significantly better.
  • Helps minimize joint damage, lowers symptoms, and prevents future problems. People taking Orencia (abatacept) had no new joint damage after two years.
  • Taking Orencia (abatacept) allows RA patients to use less prednisone, a steroid that has many side effects.
  • You can give yourself Orencia (abatacept) subcutaneously on your own at home rather than visiting a clinic or hospital.
  • Available in a prefilled autoinjector for convenient use.
Downsides
No information currently available
  • Orencia (abatacept) can be costly.
  • The IV infusion form of Orencia (abatacept) can cause a reaction, which ranges from a slight itching or warm feeling to more serious side effects such as low blood pressure and chest pain.
  • The IV infusion form of Orencia (abatacept) contains maltose, a type of sugar, that can give false high blood sugar readings with certain types of blood sugar monitors on the day of Orencia (abatacept) infusion. The self-injection subcutaneous form does not contain maltose. Talk to your doctor if you have diabetes.
  • If you need TNF inhibitors as part of your treatment, it is not recommended to take Orencia (abatacept). If you have COPD, you are at higher risk of side effects.
  • Orencia (abatacept) lowers your ability to fight infection. Your risk can increase if you take medications that lower your immune system or have an active infection. You may need to get tested for tuberculosis before starting Orencia (abatacept).
Used for
  • Chronic lymphoid leukemia
  • In patients who have received at least 1 prior therapy Chronic lymphoid leukemia
  • In patients with 17p chromosome deletion Mantle cell lymphoma
  • In previously treated patients
Dosage forms
  • Pill
  • Infusion
  • Injection
Price
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$11332
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Lowest price near you
$3912.13
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Reviews
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Side effects
The Imbruvica (Ibrutinib) FDA package insert doesn’t have numbers about how common side effects are.
10possible side effects
  • Headache
    18%
  • Common cold
    12%
  • Dizziness
    9%
  • Cough
    8%
  • Back pain
    7%
  • High blood pressure
    7%
  • Indigestion
    6%
  • Urinary tract infection
    6%
  • Rash
    4%
  • Pain in arms or legs
    3%
See more detailed side effects
Risks and warnings
No information currently available
  • High risk of infections with TNF inhibitors

    Using TNF inhibitors

  • Immunosuppression and Infections

    Taking immunosuppressive medications

    ...and 2 more risk factors

  • More COPD side effects

    COPD

See more detailed risks and warnings