Compare Imdur vs. Isordil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Imdur
(Isosorbide Mononitrate)

Isordil
(Isosorbide Dinitrate)

Relieves chest pain. Isosorbide mononitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.Relieves chest pain. Isosorbide dinitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.
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Reviews & ratings
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3.9393939393939394Imdur
Reviews for Imdur (Isosorbide Mononitrate)
48%
of people say Imdur (Isosorbide Mononitrate) is worth it
30%
say it works well
33%
say it's a big hassle
Reviews for Isordil (Isosorbide Dinitrate)
46%
2% vs. Imdur (Isosorbide Mononitrate)
24%
6% vs. Imdur (Isosorbide Mononitrate)
20%
+13% vs. Imdur (Isosorbide Mononitrate)
Side effects
ImdurIsordil
  • Headache 42%
  • Dizziness 7%
More Imdur side effects »

The Isordil FDA package insert doesn’t have numbers about how common side effects are.

More about Isordil side effects »
How it works
ImdurIsordil
Isosorbide mononitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Isosorbide dinitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.
Type of medication
ImdurIsordil
Vasodilator
Nitrate
Prescription only
Vasodilator
Nitrate
Prescription only
Available as
ImdurIsordil
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
ImdurIsordil
Risk factors for serious side effects
ImdurIsordil
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Imdur (Isosorbide Mononitrate) risks & warnings »
  • Age 65 years or older
  • Taking drugs for erectile dysfunction
  • Alcohol use
    Detailed Isordil (Isosorbide Dinitrate) risks & warnings »
    Pregnancy category
    ImdurIsordil
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Dizziness and falls may occur due to a sudden drop in blood pressure when you change positions, like from lying down or sitting to standing. This is called orthostatic hypotension. If you're sensitive to low blood pressure, change position slowly until your body is used to the medicine. If symptoms continues for more than a week, talk to your doctor. Also tell your doctor if you are taking any drugs for erectile dysfunction, as this can increase the likelihood of dizziness or falls. Drinking alcohol while on this medication may also increase the risk of dizziness or falling.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.No specific sex-related info.
    Sleep
    No specific sleep-related info.No specific sleep-related info.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    ImdurIsordil
    • Prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
    • Treats and prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
    Downsides and risks
    ImdurIsordil
    • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
    • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
    • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
    • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
    Tips from our pharmacists for people taking the medication
    ImdurIsordil
    • Can cause headaches, dizziness, lightheadedness, or fainting. Headache can be a sign that the medicine is working.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Tell your doctor if you're taking any medicine for erectile dysfunction.
    • Don't stop taking this medicine suddenly.
    • Can cause headaches, dizziness, lightheadedness, or fainting.
    • Don't drink alcohol while taking this medicine. It can make you really dizzy.
    • Tell your doctor if you're taking any medicine for erectile dysfunction.
    • Don't stop taking this medicine suddenly.
    Learn more
    More about ImdurSide effectsReviews & ratingsAlternativesFDA package insert
    More about IsordilSide effectsReviews & ratingsAlternativesFDA package insert