Compare Imdur vs. Nitrostat

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Imdur
(Isosorbide Mononitrate)

Nitrostat
(Nitroglycerin)

Relieves chest pain. Isosorbide mononitrate is good for chest pain, but you have to be able to stick to your dosing schedule or it won't work as well.Relieves chest pain. Nitroglycerin is the fastest-working medicine to relieve chest pain, but make sure to sit down before taking it.
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Reviews & ratings
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3.9393939393939394Imdur
Reviews for Imdur (Isosorbide Mononitrate)
48%
of people say Imdur (Isosorbide Mononitrate) is worth it
30%
say it works well
33%
say it's a big hassle
Reviews for Nitrostat (Nitroglycerin)
40%
8% vs. Imdur (Isosorbide Mononitrate)
50%
+20% vs. Imdur (Isosorbide Mononitrate)
21%
+12% vs. Imdur (Isosorbide Mononitrate)
Side effects
ImdurNitrostat
  • Headache 42%
  • Dizziness 7%
More Imdur side effects »
  • Headache 45%
  • Lightheadedness 2%
More Nitrostat side effects »
How it works
ImdurNitrostat
Isosorbide mononitrate is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.Nitroglycerin is a nitrate. It dilates blood vessels all over the body. This makes it less work for the heart to pump, which relieves heart-related chest pain.
Type of medication
ImdurNitrostat
Vasodilator
Nitrate
Prescription only
Vasodilator
Nitrate
Prescription only
Available as
ImdurNitrostat
  • Pill
  • Extended release
  • Dissolving tablet
  • Pill
  • Extended release
  • Patch
  • Mouth spray
  • Cream, gel, or ointment
  • Rectal gel or ointment
Used for (click to learn more)
ImdurNitrostat
Risk factors for serious side effects
ImdurNitrostat
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Imdur (Isosorbide Mononitrate) risks & warnings »
  • Concurrent use of erectile dysfunction medicine
  • Age 65 years or older
  • Alcohol use
  • Long term use
Detailed Nitrostat (Nitroglycerin) risks & warnings »
Pregnancy category
ImdurNitrostat
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
CFDA pregnancy category (Weigh risks vs. benefits)

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

See the FDA package insert
Alcohol
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Don't drink alcohol while taking this medicine. It can make dizziness worse.
Food
No specific food-related info.No specific food-related info.
Kidneys and liver
No specific kidneys and liver-related info.No specific kidneys and liver-related info.
Sex
No specific sex-related info.No specific sex-related info.
Sleep
No specific sleep-related info.No specific sleep-related info.
Weight
No specific weight-related info.No specific weight-related info.
Upsides and benefits
ImdurNitrostat
  • Prevents heart-related chest pain (angina) from the narrowing of heart blood vessels (coronary artery disease).
  • First-choice treatment for quick relief of heart-related chest pain (angina).
  • Can also be used to prevent chest pain from happening.
  • Available in various forms that take effect at different speeds and stay in your system for different lengths of time. Sublingual form works the fastest (1-3 minutes) but lasts the shortest in your body (25 minutes), while the patch form takes the longest to start working (30 minutes) but lasts the longest (10-12 hours). Your doctor can help you find the one that's best for you.
Downsides and risks
ImdurNitrostat
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
  • You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule for the extended-release, ointment, and patch forms to prevent this from happening.
  • Headaches are normal with this medicine and they go away as your body gets used to it, but they can be severe or not tolerable for some people.
Tips from our pharmacists for people taking the medication
ImdurNitrostat
  • Can cause headaches, dizziness, lightheadedness, or fainting. Headache can be a sign that the medicine is working.
  • Don't drink alcohol while taking this medicine. It can make you really dizzy.
  • Don't stop taking this medicine suddenly.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
  • Can cause headaches, dizziness, lightheadedness, or fainting. Sit down before taking this medicine in case you get dizzy.
  • Take it exactly as instructed by your doctor.
  • Usually relieves chest pain in 1 to 5 minutes. If pain continues, you can take up to 3 doses, with 5 minutes in between each dose. Call 911 or go to the hospital if you've taken a second dose.
  • Don't drink alcohol while taking this medicine. It can make dizziness worse.
  • Tell your doctor if you're taking any medicine for erectile dysfunction.
Learn more
More about ImdurSide effectsReviews & ratingsAlternativesFDA package insert
More about NitrostatSide effectsReviews & ratingsAlternativesFDA package insert