Compare Imitrex vs. Amerge

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Imitrex (Sumatriptan)

Prescription only

Amerge (naratriptan)

Prescription only
Treats migraine headaches.

Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.

5.3/ 7 average rating with 31 reviewsforImitrex
Treats migraine headaches.

Amerge (naratriptan) isn't as good as other similar medications for migraines, but can be good if other drugs haven't worked for you.

Upsides
  • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
  • A combination of forms can be used if symptoms do not improve.
  • The nasal spray and injectable forms work very quickly.
  • It's generally safe to use if you are pregnant.
  • Comes in a generic form, so it can be pretty cheap.
  • Amerge (naratriptan) is a good alternative to other triptans since it's less likely to cause side effects and if other triptans haven't worked for you.
  • Available as a generic, which makes it cheaper than other medicines and is more likely to be covered by insurances.
  • Amerge (naratriptan) comes in two different strengths.
Downsides
  • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
  • Does not prevent migraine headaches; it only treats them once they start.
  • Must wait 1 hour before using second injection.
  • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
  • Need to have your blood pressure checked often, especially if you're pregnant.
  • Amerge (naratriptan) is only available as a pill that must be swallowed, so it might not be good if you have trouble swallowing when you have a migraine.
  • Unlike other migraine medications, you have to wait for 4 hours before you can take the second dose of Amerge (naratriptan).
  • Amerge (naratriptan) is not as good as other medications for treating nausea that can happen with migraines.
Used for
Dosage forms
  • Pill
  • Injection
  • Nasal spray
  • Pill
Price
Lowest price near you
$12.4
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Lowest price near you
$26.03
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Reviews
31 
74%
think this treatment is worth it
68%
think this treatment works well
19%
think this treatment is a hassle

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Side effects
6possible side effects
  • Pain and other pressure sensations
    6%
  • Atypical sensations
    5%
  • Paresthesia (all types)
    3%
  • Sensation warm/cold
    3%
  • Pain - location specified
    2%
  • Malaise/fatigue
    2%
See more detailed side effects
6possible side effects
  • Stomach problems
    6%
  • Nausea
    4%
  • Nervous system issues
    4%
  • Unusual sensation
    2%
  • Fatigue or uneasiness
    2%
  • Pain and pressure sensation
    2%
See more detailed side effects
Risks and warnings
  • Tightening of blood vessels (myocardial angina, ischemia, or infarction)

    History of heart problems

    ...and 5 more risk factors

  • Stroke

    History of heart problems

    ...and 5 more risk factors

  • Serotonin syndrome

    Patients taking SSRIs and SNRIs

  • High blood pressure

    History of high blood pressure

  • Seizures

    History of seizures

See more detailed risks and warnings
  • Heart attack

    Heart disease

    ...and 2 more risk factors

  • Stroke

    History of a stroke

  • Medication overuse headache

    Using Amerge (naratriptan) for more than 10 days a month

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Increased blood pressure

    Uncontrolled high blood pressure

  • Blood vessel issues

    High blood pressure

    ...and 2 more risk factors

See more detailed risks and warnings